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How a Single Workout Affects Gut Bugs in Women With Different Fitness Levels and Body Types
Sponsor: George Washington University
Summary
This study aims to elucidate the differences in the gut microbiome functional activity and metabolome in adult premenopausal women with distinctive fitness levels and BMIs (with obesity, w/o obesity). The specific aims are as follows: * Aim 1: To examine the effects of acute aerobic exercise at 60-70% heart rate reserve (HRRmax) for 30 minutes bout on changes in the abundance of SCFA-producing bacteria and their functional downstream metabolic activity. * Aim 2: To examine the effects of acute aerobic exercise at 60-70% HRRmax 30-minute bout on changes in GM-released SCFA concentrations in stool and plasmatic metabolome.
Official title: The Acute Effects of an Endurance Exercise Bout the Gut Microbiome and Gut-derived Metabolome in Women's Distinct Fitness and Body Mass Indexes
Key Details
Gender
FEMALE
Age Range
21 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2024-10-16
Completion Date
2027-10-16
Last Updated
2025-07-24
Healthy Volunteers
Yes
Interventions
Aerobic Exercise
30-minute exercise bout in a cycle ergometer at 60 to 70% of the Heart Rate Reserve (HRR) and corresponding power (watts).
Locations (1)
Milken Institute School of Public Health, The George Washington University
Washington D.C., District of Columbia, United States