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RECRUITING
NCT06779188
EARLY_PHASE1

Examining the Effects of Theta Burst TMS on Brain Connectivity and Balance Ability in Older Adults With Balance Problems

Sponsor: Weinberg Medical Physics LLC

View on ClinicalTrials.gov

Summary

The goal of this study is to learn if manipulating the brain using magnets works to treat balance impairment, a major cause of falls, in older adults with balance problems. The technique to manipulate the brain using magnets is known as transcranial magnetic stimulation or TMS. The main questions this study aims to answer are: * How does TMS change communication between brain areas? * Does TMS improve balance ability in older adults with balance problems? Researchers will compare the TMS group to a placebo group to see if manipulating the brain using magnets works to treat balance impairment. Participants will: * Receive TMS or placebo stimulation for 4 weeks. * Visit the laboratory for checkups and tests 3 times.

Official title: Treating Balance Impairment of the Elderly With TMS-induced Brain Connectivity

Key Details

Gender

All

Age Range

65 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2025-05-06

Completion Date

2026-05-31

Last Updated

2025-05-15

Healthy Volunteers

No

Interventions

DEVICE

Transcranial Magnetic Stimulation

TMS (in the form of theta burst stimulations) will be delivered over Supplementary Motor Area while the subject is seated in the Treatment group. TMS is capable to induce neuroplastic facilitatory changes in the brain that last beyond the duration of stimulation. TMS will be delivered once daily, 5 days per week, for 4 weeks.

DEVICE

Transcranial Magnetic Stimulation Sham

Sham TMS will be delivered in the sham group using a sham coil once daily, 5 days per week, for 4 weeks.

Locations (1)

The Center for Neuromotor and Biomechanics Research at the University of Houston

Houston, Texas, United States