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The Effectiveness of Two Distinct Ventilation Strategies Escalating Positive End Expiratory Pressure (PEEP) and Lung Recruitment Maneuvers in Improving Oxygenation
Sponsor: Ain Shams University
Summary
This study evaluates and compares the effectiveness of two distinct ventilation strategies-escalating PEEP and lung recruitment maneuvers-in improving oxygenation (i.e., managing hypoxemia) in COPD patients undergoing VATS.
Official title: Comparative Study of Escalating PEEP (Positive End Expiratory Pressure) vs. Lung Recruitment by Sustained Inflation Strategies for Managing Hypoxemia in COPD Patients Undergoing Video-Assisted Thoracoscopic Surgery (VATS)
Key Details
Gender
All
Age Range
20 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-01-30
Completion Date
2025-07-27
Last Updated
2025-03-11
Healthy Volunteers
No
Interventions
Escalating PEEP
Typically, an initial PEEP of 5 cm H₂O, then PEEP is increased in 2-3 cm H₂O increments while monitoring the patient's response (oxygenation, hemodynamics, and lung compliance).
Sustained inflation
Set the ventilator to CPAP mode and increase the pressure to 30 cm H2O for 30 s.
Locations (1)
Ain Shams university
Cairo, Egypt, Egypt