Clinical Research Directory

Inclusion Criteria: * Female * Generally healthy * Aged 55-75 years * BMI 18.5-34.9 kg/m2 * Fitzpatrick Skin type II-IV * Consume a typical Western diet (low in polyphenols-rich foods and fiber) * Willing to maintain habitual dietary and exercise patterns for the study duration * Willing to maintain normal skin care products and pattern for the duration of the study * Willing to come to study visits without any makeup and skin products on * Subjects must read and sign the Institutional Review Board-approved written informed consent prior to the initiation of any study specific procedures or enrollment. A subject will be excluded for any condition that might compromise the ability to give truly informed consent. Exclusion Criteria: * Vegetarian/vegan * Known nut allergy * Skin-related prescription medication, supplements or non-prescription cosmeceutical agents * Initiation of topical or oral prescription steroids and/or anti-inflammatory medications within 30 days prior to study enrollment * Excessive exposure to either natural or artificial sunlight * Screening laboratory values outside of the normal range that is considered clinically significant for study participation by the investigator * Documented chronic disease * Taking medications or supplements known to affect gut microbiota composition (antibiotics within the past 3 months, probiotics, fiber, etc.) * Taking exogenous hormones (e.g. hormone replacement therapy) * Recent weight fluctuations (\>10% in the last 6 months) * Smoker or living with a smoker * Use of \>20 g of alcohol per day * Unable or unwilling to comply with the study protocol (including unwillingness to avoid nuts for the whole duration of the study) * Unable to provide consent * Pregnancy and/or lactation