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NCT07048548

Assessment of THL and Potential Risk of Hypothyroidism in Healthcare Workers Exposed to Low-dose Ionizing Radiation

Sponsor: Superior University

View on ClinicalTrials.gov

Summary

"This study is designed to evaluate the thyroid health of healthcare workers exposed to low-dose ionizing radiation at INMOL Cancer Hospital, Lahore. Specifically, it investigates whether prolonged occupational exposure in radiology and nuclear medicine departments is associated with altered thyroid hormone levels or an increased risk of hypothyroidism. The thyroid gland is highly sensitive to radiation, and existing literature suggests a possible link between occupational exposure and thyroid dysfunction.

Official title: Assessment of Thyroid Hormone Levels and Potential Risk of Hypothyroidism in Healthcare Workers Exposed to Low-dose Ionizing Radiation

Key Details

Gender

All

Age Range

20 Years - 40 Years

Study Type

OBSERVATIONAL

Enrollment

44

Start Date

2025-03-18

Completion Date

2026-02-01

Last Updated

2025-07-02

Healthy Volunteers

No

Conditions

Interventions

BEHAVIORAL

Thyroid Function Monitoring

This study will include healthcare professionals from the radiology and nuclear medicine departments at INMOL Cancer Hospital with at least one year of radiation exposure. A total of 44 participants will be selected through purposive sampling. Data will be collected using a structured questionnaire and blood tests for thyroid hormones (TSH, T3, T4) to assess thyroid function. Blood analysis will be conducted using CLIA or ELISA methods. The aim is to detect any association between low-dose radiation exposure and thyroid dysfunction.

Locations (1)

INMOL hospital

Lahore, Punjab Province, Pakistan