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Serum Surfactant Protein-D as Predictor of Disease Severity in Hospitalized COPD Patients
Sponsor: Assiut University
Summary
evaluation of the serum levels of surfactant protein-D (SP-D), C-reactive protein (CRP), fibrinogen, and peripheral blood neutrophilic and eosinophilic counts in patients with COPD correlation of these biomarkers with clinical, functional, and radiological parameters
Official title: Serum Surfactant Protein-D and Inflammatory Biomarkers as Predictors of Disease Severity in Hospitalized Chronic Obstructive Pulmonary Disease (COPD) Patients
Key Details
Gender
All
Age Range
40 Years - 88 Years
Study Type
OBSERVATIONAL
Enrollment
75
Start Date
2025-12-01
Completion Date
2027-01-01
Last Updated
2025-09-10
Healthy Volunteers
Not specified
Conditions
Interventions
Serum Surfactant Protein-D
Several studies support the use of SP-D as a marker of systemic inflammation and lung tissue damage in COPD.Measuring serum SP-D could provide a valuable tool for early detection, monitoring progression, and personalizing management of COPD patients.Surfactant protein D (SP D) as a prognostic biomarker needs further studies to validate its clinical applicability