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RECRUITING
NCT07202065
PHASE2/PHASE3

Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Dosing Immunoglobulin (Dose Ig)

Sponsor: Monash University

View on ClinicalTrials.gov

Summary

This study is being conducted to find out how safe and effective different strategies of infection prevention are in comparison to each other, for preventing infection in patients with blood cancers. The best way to find out this information is to directly compare the effect of different treatment strategies in patients with blood cancers. We want to know how these different treatments impact on your health and your use of healthcare services. This research project uses an Adaptive Platform Design. This design allows the researchers to compare multiple infection prevention strategies within the same trial at the same time (rather than running separate trials), to analyse results as the trial occurs and to add new research questions during the course of the trial. The treatments that you may receive as part of the study will be determined by which domain(s) of the platform you participate in. By combining data collected within each domain as part of the platform, the researchers can investigate and compare treatment strategies and infection outcomes across a broader range of participants.

Official title: Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy (Dose-Ig)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

900

Start Date

2025-04-28

Completion Date

2027-03-31

Last Updated

2025-10-07

Healthy Volunteers

No

Interventions

BIOLOGICAL

Immune Globulin Intravenous

Participants will be treated with intravenous immunoglobulin monthly (every 4 weeks ± 1 week).

Locations (3)

Royal Adelaide Hospital

Adelaide, South Australia, Australia

Austin Hospital

Melbourne, Victoria, Australia

Northern Health

Melbourne, Victoria, Australia