Clinical Research Directory

Test-Retest Reliability And Validation For End-Tidal Carbon Dioxide Measurement (PetCO2) During Rest And Low-Loaded Steady State Work Using A Portable Capnograph.

Sponsor: Linkoeping University

Summary

The goal of this observational study is to investigate exhaled carbon dioxide measuring during rest and low-loaded work using a portable device (capnograph) and standard of care apparatus during a cardiopulmonary exercise test (CPET) in healthy volunteers. The study aims to answer: How reliable is exhaled end-tidal carbon dioxide measurement for an individual over time using both standard of care apparatus and a portable device during an ergometer test? Do the measurements correlate between the portable device and standard of care apparatus? How do changes in breathing instructions and placement of sampling cannula affect the measurements from the portable device (capnograph)? How is the reliability over time of other well established values from a cardio pulmonary exercise test? Participants will be asked to perform a modified cardiopulmonary exercise test on an ergometer twice, separated in time (1-4 weeks). Measurements are sampled alternating standard of care apparatus and a portable capnograph at rest and during low-loaded work.

Official title: Measurement Of End-Tidal Carbon Dioxide Partial Pressure (PetCO2) Using A Portable Capnograph During Rest and Low-Loaded Steady State Work On An Ergometer: Test Of Reproducibility and Validation Against Standard Of Care Measurement During a Cardio Pulmonary Exercise Test.

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