Clinical Research Directory

Inclusion Criteria: * Rapid Assessment of Physical Activity scores between 3 and 5 * Able to don and doff the weighted vest * Access to a smart phone and ability to navigate the phone to enter and manage a zoom intervention * Commitment and availability to attend a virtual 40-minute intervention 3x per week for 12 weeks Exclusion Criteria: * Contraindications to radiation exposure (e.g. Women who are pregnant, previous high radiation exposure) * Bleeding disorders * Lower extremity trauma/surgery/injury or neuropathy that would impact muscle structure and function or ability to complete exercise intervention * Diabetes mellitus, cardiovascular disease, peripheral vascular disease, cancer, stage 4 hypertension, anemia, connective tissue disorder * Neurological disorder (e.g. stroke, Parkinson's disease, multiple sclerosis, spinal cord injury) * Medications: insulin, glucagon-like peptide-1 (GLP1) agonists, sex hormone replacement therapy, chronic NSAIDs, anticoagulation therapy, cholesterol lowering medications such as statins * Unable to safely perform the progressive resistance exercise (e.g. Vestibular or balance issues that make performing the intervention unsafe, severe osteoporosis or general fragility that limits weighted vest tolerance)