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Effectiveness of Unilateral Transversus Abdominis Plane (TAP) Block vs Bilateral TAP Block in Patients Undergoing Laparoscopic Cholecystectomy.
Sponsor: King Edward Medical University
Summary
In this study, patients undergoing laparoscopic cholecystectomy will be randomly divided into 2 groups after consent. Group A patients will be administered a one-sided (right unilateral) regional TAP block and group B patients will be administered the same block on both sides (bilateral) and the effects in terms of post surgery pain during the 1st 24 hours, nausea vomiting, and the need and dosage of intravenous analgesic and antiemetic will be studied to see whether one technique is superior to the other or not.
Official title: Comparison of Efficacy of Unilateral Transversus Abdominis Plane (TAP) Block Versus Bilateral Transversus Abdominis Plane (TAP) Block in Patients Undergoing Laparoscopic Cholecystectomy.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
82
Start Date
2025-11-04
Completion Date
2026-04-04
Last Updated
2026-04-06
Healthy Volunteers
No
Conditions
Interventions
Unilateral Transversus abdominis plane (TAP) block with 0.25 % bupivacaine
TAP block is a regional anesthesia technique used for post-operative analgesia in abdominal surgeries. TAP block was first described by Rafi et al in 2001, as a regional block, in which local anesthesia is injected through triangle of petit to achieve analgesia of the T6 to L1 thoracolumbar nerves as they pass through the plane between internal oblique and transversus abdominis muscles. This blocks the sensory nerves in the anterolateral abdominal wall. Right Unilateral TAP block has been used as a part of multimodal analgesia in Lap chole (LC), with favorable results.
Bilateral Transversus abdominis plane (TAP) block with 0.25 % bupivacaine
TAP block is a regional anesthesia technique used for post-operative analgesia in abdominal surgeries. TAP block was first described by Rafi et al in 2001, as a regional block, in which local anesthesia is injected through triangle of petit to achieve analgesia of the T6 to L1 thoracolumbar nerves as they pass through the plane between internal oblique and transversus abdominis muscles. This blocks the sensory nerves in the anterolateral abdominal wall. Bilateral TAP block can be used as a part of multimodal analgesia in Lap chole (LC), because two of the ports (epigastric and umbilical) in Lap chole are in the midline and hence receive sensory supply from both right and left side.
Locations (1)
King Edward Medical University/ Mayo Hospital, Lahore.
Lahore, Punjab Province, Pakistan