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RECRUITING
NCT07526909
NA

Effect of Different Meal Types Given Before Exercise on Plasma Amino Acid Levels and Metabolic Control Parameters in Classical Phenylketonuria Patients Undergoing Aerobic and Resistance Exercises

Sponsor: Hacettepe University

View on ClinicalTrials.gov

Summary

This study will be the first in the literature to evaluate the relationship between aerobic and resistance exercises, plasma amino acid levels, metabolic control of patients, and the metabolic response to exercise with different types of meals in patients with Phenylketonuria (PKU). In patients with phenylketonuria, the aim is to determine which pre-exercise dietary recommendations are more physiologically appropriate and ideal for achieving good metabolic control. In the literature, there are very few studies examining the effects of exercise on plasma amino acid levels and metabolic parameters in PKU patients.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

10

Start Date

2025-10-01

Completion Date

2026-07-15

Last Updated

2026-04-16

Healthy Volunteers

No

Conditions

Interventions

BEHAVIORAL

Aerobic Exercise

Participants performed 30 minutes of moderate-intensity aerobic exercise on a treadmill at 80% of maximum heart rate with a 3% incline.

BEHAVIORAL

Resistance Exercise

Participants performed a resistance exercise session including 3 sets of 10 repetitions of crunch, push-up, forward lunge, and squat exercises.

OTHER

Water

Participants consumed 200 ml of water prior to the exercise session.

DIETARY_SUPPLEMENT

Carbohydrates

Participants consumed carbohydrates at a dose of 1 g/kg/hour prior to the exercise session.

DIETARY_SUPPLEMENT

Protein

Participants consumed protein equivalent to 0.4 g/kg/hour (amino acids) prior to the exercise session.

Locations (1)

Hacettepe University

Ankara, Ankara, Turkey (Türkiye)