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COMPLETED
NCT07600138
NA

Effects of Carbohydrates Versus Carbohydrates + Protein on Resistance Training Outcomes

Sponsor: Auburn University

View on ClinicalTrials.gov

Summary

Higher energy and carbohydrate intakes have been hypothesized to enhance resistance training adaptations, yet empirical evidence remains mixed. This study investigated whether supplemental carbohydrate-energy intake improves muscle hypertrophy, strength, and fatigue resistance in resistance-trained men. Twenty resistance-trained men completed a quasi-randomized, double-blinded, counterbalanced crossover trial. Participants consumed either a daily protein-only supplement (30 g protein, 4 g carbohydrate) or a daily protein-plus-carbohydrate supplement (30 g protein, 54 g carbohydrate) for 8 weeks each, followed by crossover, while continuing their habitual training and diet. Primary outcomes included lean mass (dual-energy x-ray absorptiometry), muscle thickness and cross-sectional area (ultrasound), back squat one-repetition maximum, knee extensor peak torque, and fatigue index. The carbohydrate-protein supplement produced significantly higher daily energy and carbohydrate intake compared to the protein-only supplement, with no differences in protein intake, fat intake, or training volume. No significant between-condition differences were observed for any outcome. These results suggest that modest increases in carbohydrate-energy intake outside of an energy deficit are unlikely to meaningfully enhance muscle hypertrophy, strength, or fatigue resistance in trained men.

Key Details

Gender

MALE

Age Range

18 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

25

Start Date

2025-05-12

Completion Date

2025-09-16

Last Updated

2026-05-20

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

CHO

Daily consumption of a whey protein and maltodextrin mixture providing 30 g protein, 54 g carbohydrate, and 2 g fat per 92 g serving for 8 weeks

DIETARY_SUPPLEMENT

PRO

Daily consumption of a whey protein blend providing 30 g protein, 4 g carbohydrate, and 2 g fat per 39 g serving for 8 weeks.

Locations (1)

School of Kinesiology

Auburn, Alabama, United States