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The Influence of Anatomical Characteristics and Orthodontic Force on Pulpal Oxygen Saturation: A Clinical Study Using Cone-Beam Computed Tomography (CBCT)
Sponsor: Can Tho University of Medicine and Pharmacy
Summary
The primary objective of this clinical protocol is to evaluate and compare the physiological responses of dental pulp to two different magnitudes of orthodontic force during active orthodontic treatment. Participants are assigned to either a 150g orthodontic force group (experimental group) or a 50g orthodontic force group (active comparator group). Orthodontic Force Application: A continuous orthodontic force of approximately 150g is applied to the target teeth in the experimental group, whereas a continuous force of approximately 50g is applied to the target teeth in the active comparator group. The magnitude of the applied force is verified using a tension gauge to ensure standardized force delivery. Pulse Oximetry (SpO₂) Measurement: Pulp oxygen saturation (SpO₂) is assessed using the same standardized protocol in both groups. The target teeth are isolated with cotton rolls to control moisture, and the dental chair light is turned off to minimize optical interference with the pulse oximeter. Three consecutive measurements are obtained at each assessment time point, and the mean value is recorded for analysis. This standardized protocol enables comparison of pulp oxygen saturation responses between teeth subjected to 150g and 50g orthodontic forces while minimizing variability related to force application and measurement procedures.
Key Details
Gender
All
Age Range
15 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
38
Start Date
2025-05-01
Completion Date
2026-09-01
Last Updated
2026-09-11
Healthy Volunteers
Yes
Conditions
Interventions
150g Orthodontic Force Application
A controlled mechanical orthodontic force of approximately 150g is applied to the target teeth and verified using a tension gauge. The force is applied to induce orthodontic tooth movement, and pulp oxygen saturation (SpO₂) is monitored at predefined follow-up time points.
50g Orthodontic Force Application
A controlled mechanical orthodontic force of approximately 50g is applied to the target teeth and verified using a tension gauge. The force serves as the active comparator, and pulp oxygen saturation (SpO₂) is monitored at the same predefined follow-up time points as in the 150g group.
Locations (1)
Can Tho University of Medicine and Pharmacy
Can Tho, Vietnam