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Senescence in Myocardial Infarction
Sponsor: South Tees Hospitals NHS Foundation Trust
Summary
The investigators of this study have found that after a heart attack, some heart cells rapidly age (become senescent) and release proteins that make the heart disease worse. The investigators of this study would like to check for these aged-cell proteins in participants who have coronary artery bypass graft (CABG) surgery after a recent heart attack or to treat more stable heart disease. The investigators will do this by taking blood samples and a sample of normally discarded heart tissue from each group of participants. This might help tell us who is at the highest risk of developing heart disease and how people recover from a heart attack.
Official title: Coronary Artery Bypass Surgery After Myocardial Infarction: Identifying Clinical Outcomes by Analysing the Senescence Associated Secretory Phenotype
Key Details
Gender
All
Age Range
40 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
22
Start Date
2024-05-08
Completion Date
2026-02-26
Last Updated
2026-07-09
Healthy Volunteers
No
Conditions
Locations (1)
South Tees Hospitals NHS Foundation Trust
Middlesbrough, United Kingdom