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TERMINATED
NCT07693712

Senescence in Myocardial Infarction

Sponsor: South Tees Hospitals NHS Foundation Trust

View on ClinicalTrials.gov

Summary

The investigators of this study have found that after a heart attack, some heart cells rapidly age (become senescent) and release proteins that make the heart disease worse. The investigators of this study would like to check for these aged-cell proteins in participants who have coronary artery bypass graft (CABG) surgery after a recent heart attack or to treat more stable heart disease. The investigators will do this by taking blood samples and a sample of normally discarded heart tissue from each group of participants. This might help tell us who is at the highest risk of developing heart disease and how people recover from a heart attack.

Official title: Coronary Artery Bypass Surgery After Myocardial Infarction: Identifying Clinical Outcomes by Analysing the Senescence Associated Secretory Phenotype

Key Details

Gender

All

Age Range

40 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

22

Start Date

2024-05-08

Completion Date

2026-02-26

Last Updated

2026-07-09

Healthy Volunteers

No

Locations (1)

South Tees Hospitals NHS Foundation Trust

Middlesbrough, United Kingdom