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NOT YET RECRUITING
NCT07722403
NA

Acute Autonomic Responses During and After BFR Training

Sponsor: Egas Moniz - Cooperativa de Ensino Superior, CRL

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to compare how the body's nervous system responds to two different types of leg exercise in young and older adults. One type is low-intensity exercise with blood flow restriction (BFR) , where a cuff partially reduces blood flow to the legs during exercise. The other type is traditional high-intensity resistance training (HIRT), which uses heavier weights. The main questions it aims to answer are: Does low-intensity exercise with BFR cause less stress on the nervous system during exercise compared to high-intensity training? Does low-intensity exercise with BFR lead to faster recovery of the nervous system after exercise compared to high-intensity training? Do these responses differ between young adults and older adults? Researchers will compare low-intensity exercise with BFR to high-intensity training to see which approach is gentler on the nervous system during and after exercise. Participants will: Attend three visits to the research lab Complete a strength test on leg exercise machines Perform two separate exercise sessions: one with low-intensity exercise and BFR, and one with high-intensity training Have their heart rate, blood pressure, and heart rate variability monitored continuously during and after each exercise session

Official title: Acute Cardiac Autonomic Responses During And Following Low-Intensity Blood Flow Restriction Resistance Exercise Versus Conventional High-Intensity Resistance Training In Young And Older Adults

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

48

Start Date

2026-10-05

Completion Date

2027-06-25

Last Updated

2026-07-23

Healthy Volunteers

Yes

Interventions

OTHER

High-Intensity Resistance Training (HIRT)

Participants perform bilateral knee extensions and leg curls at 75% of their one-repetition maximum (1RM). The protocol consists of 3 sets of 10 repetitions with 2-minute rest intervals between sets. Total exercise duration is approximately 30 minutes.

OTHER

Low-Intensity Resistance Training with Blood Flow Restriction (LIRT-BFR)

Participants perform bilateral knee extensions and leg curls at 30% of their one-repetition maximum (1RM) while a pneumatic cuff is applied to the most proximal portion of both thighs. The cuff is inflated to 1.3 times the individual's ankle systolic blood pressure. The protocol consists of 4 sets of 20 repetitions with 30-second rest intervals between sets. Total exercise duration is approximately 30 minutes. Cuff pressure is maintained continuously throughout sets and rest periods and is released immediately after the final repetition.

Locations (1)

Egas Moniz School of Health and Science

Almada, Monte Da Caparica, Portugal