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Memory Enhancement in Aging With Closed-Loop tACS
Sponsor: Boston University Charles River Campus
Summary
This project optimizes high-resolution tACS to improve memory in healthy older adults, advancing drug-free approaches for ADRD. We test stimulation schedules and develop an adaptive, brain-guided tACS system to strengthen memory-supporting networks.
Official title: Personalized Memory Enhancement in Aging: Pattern-Optimized tACS With Closed-Loop Precision Modulation
Key Details
Gender
All
Age Range
65 Years - Any
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2028-05-01
Completion Date
2031-01-31
Last Updated
2026-07-23
Healthy Volunteers
Yes
Conditions
Interventions
Peak Frequency
Device: High definition transcranial electrical current stimulation Low-intensity, noninvasive application of electrical current to the human scalp tailored to individual peak frequency with the goal of modulating levels of neuronal excitability.
Phase Lag
Device: High definition transcranial electrical current stimulation Low-intensity, noninvasive application of electrical current to the human scalp tailored to individual phase lag with the goal of modulating levels of neuronal excitability.
Peak Frequency + Phase Lag
Device: High definition transcranial electrical current stimulation Low-intensity, noninvasive application of electrical current to the human scalp tailored to individual peak frequency and phase lag with the goal of modulating levels of neuronal excitability.
Non-Adpative
Device: High definition transcranial electrical current stimulation Low-intensity, noninvasive application of electrical current to the human scalp not tailored to individual peak frequency or phase lag with the goal of modulating levels of neuronal excitability.