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NOT YET RECRUITING
NCT07726498

STRIDE: Strength of The Calf Muscles and Their Role In Declining Effectiveness of Movement With Aging

Sponsor: University of Leicester

View on ClinicalTrials.gov

Summary

The calf muscles (plantarflexors) are the most important muscles for walking, running and daily activities. Weakness of these muscles through aging and disease significantly impact a person's ability to walk and complete daily activities. By assessing calf strength, it is possible to identify people at risk of falls, and a condition called sarcopenia (which means loss of muscle mass, strength and function). Unfortunately, most of the studies that have examined this have used specialist equipment unavailable to hospital staff. Our study aims to use commercially available equipment to explore the relationship between plantarflexor muscle strength and physical performance in adults living with or without sarcopenia, including those at risk of it. The study will determine if stronger/weaker calf muscles associated with sarcopenia influence the ability to walk and do things more easily. We will complete strength tests of the calf, thigh and hand, assess walking using a special camera system, use an ultrasound scan to look at the Achilles tendon, use a scan to look at how stiff your calf muscles are, assess your body composition, complete a physical performance test and some questionnaires. Each participant will complete the measures during one clinic visit

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2026-08

Completion Date

2028-02-29

Last Updated

2026-07-24

Healthy Volunteers

Yes

Interventions

OTHER

No intervention (observational study)

No intervention (observational study)

Locations (1)

University of Leicester

Leicester, United Kingdom