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NOT YET RECRUITING
NCT07727369
NA

RePer-AGE: Reorganization of Visuo-cognitive Functions Based on Peripheral Vision With Aging

Sponsor: University Hospital, Grenoble

View on ClinicalTrials.gov

Summary

The RePer-AGE study investigates how central and peripheral vision contribute to visual recognition and how these mechanisms change with normal aging. The study is based on the hypothesis that peripheral vision provides rapid global information that supports visual recognition through predictive mechanisms. Healthy young adults (18-30 years) and older adults (60-85 years) will undergo visual psychophysical testing, ophthalmological examinations, and, for a subset of participants, functional magnetic resonance imaging (fMRI). The results are expected to improve our understanding of age-related changes in visuo-cognitive functions and provide reference data for future studies on age-related visual disorders.

Key Details

Gender

All

Age Range

18 Years - 85 Years

Study Type

INTERVENTIONAL

Enrollment

160

Start Date

2026-09-01

Completion Date

2030-09

Last Updated

2026-07-27

Healthy Volunteers

Yes

Interventions

BEHAVIORAL

Psychophysical visual recognition tasks

Computerized visual recognition tasks assessing the respective contributions of central and peripheral vision to scene recognition and predictive visual processing.

DIAGNOSTIC_TEST

Ophthalmological assessment

Ophthalmological examinations including retinal sensitivity (Humphrey automated perimetry) and low-luminance visual acuity.

DIAGNOSTIC_TEST

Functional magnetic resonance imaging (fMRI)

Functional MRI performed during psychophysical visual recognition tasks to assess brain activity associated with visual recognition and predictive visual processing.

Locations (1)

CHU Grenoble Alpes

Grenoble, Isère, France