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Oxytocin in Postmenopausal Women
Sponsor: University Hospital, Basel, Switzerland
Summary
The aim of the present study is to assess whether cumulative endogenous neurophysin I secretion over one month differs between premenopausal and postmenopausal women. Using repeated measurements of neurophysin-I (NP-I, equimolar surrogate marker of oxytocin) across defined physiological time points, this study investigates oxytocin system regulation under cyclic and non-cyclic hormonal conditions. The primary hypothesis is that cumulative NP-I release, expressed as the area under the curve (AUC) is lower in the postmenopausal group compared to the premenopausal group.
Official title: Circulating Oxytocin and Its Clinical Correlates in Postmenopausal Women Compared With Premenopausal Controls - The OxyMENO Study
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2026-08-20
Completion Date
2027-09-01
Last Updated
2026-08-24
Healthy Volunteers
No
Conditions
Interventions
Repeated assessments
This study is an observational investigation involving repeated venous blood sampling and non-invasive clinical assessments ov four study visits.
Locations (1)
University Hospital Basel
Basel, Canton of Basel-City, Switzerland