Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
COMPLETED
NCT07743333
PHASE4

Nebulized Lidocaine And Ketamine Before Fiberoptic Bronchoscopy

Sponsor: Alexandria University

View on ClinicalTrials.gov

Summary

The current study is looked for the comparison between nebulized lidocaine and ketamine, nebulized lidocaine, and usual lidocaine spray in the oral and nasal cavities before flexible bronchoscopy. The investigators are looking for different outcomes including mainly cough suppression during the procedure, patient tolerance and discomfort, operator and patients' satisfaction, and safety of the use of these medications especially regarding nebulized ketamine.

Official title: Nebulized Lidocaine And Ketamine As Premedication Before Fiberoptic Bronchoscopy: A Case-Control Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

134

Start Date

2024-09-01

Completion Date

2025-02-28

Last Updated

2026-08-03

Healthy Volunteers

No

Interventions

DRUG

Nebulized lidocaine and ketamine

This group received nebulization of lidocaine (dose of 60 mg) and ketamine (dose of 150 mg) each in separate nebulization before FOB as premedication. The patients were followed up before (just after nebulization), during and after FOB regarding hemodynamic satbility (as measured by blood pressure), heart rate and oxygen saturation.

DRUG

Nebulized Lidocaine

This group received nebulization of lidocaine (dose of 60 mg) only before FOB as premedication. The patients were followed up before, during and after FOB regarding hemodynamic satbility (measured by blood pressure), heart rate and O2 saturation.

DRUG

Lidocaine spray (2%)

This group received lidocaine spray (2%) alone for the oral and nasal cavities before FOB as premedication. The patients were followed up before, during and after FOB regarding hemodynamic satbility (measured by blood pressure), heart rate and O2 saturation.

Locations (1)

Alexandria University Faculty of Medicine

Alexandria, Alexandria Governorate, Egypt