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10% Dextrose Versus Triamcinolone Injections After Pulsed Radiofrequency for Herniated Nucleus Pulposus
Sponsor: Indonesia University
Summary
Lumbar herniated nucleus pulposus (HNP) is a common cause of chronic low back pain and radiculopathy. Transforaminal epidural steroid injection is commonly used as an adjuvant following pulsed radiofrequency (PRF) treatment but is associated with potential steroid-related adverse effects. Ten percent dextrose has been proposed as a regenerative, non-steroidal alternative. This single-blind randomized controlled trial compares the effectiveness of transforaminal epidural 10% dextrose versus triamcinolone administered after PRF in reducing pain, disability, and neuropathic pain in patients with lumbar HNP over a 14-day follow-up period.
Official title: Comparison Between 10% Dextrose Injection and Triamcinolone as an Adjuvant to Pulsed Radiofrequency of the Dorsal Root Ganglion in Patients With Herniated Nucleus Pulposus
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2025-12-05
Completion Date
2026-06-03
Last Updated
2026-08-11
Healthy Volunteers
No
Conditions
Interventions
10% Dextrose Injection
Injection of 10% dextrose administered as an adjuvant following pulsed radiofrequency of the dorsal root ganglion.
Triamcinolone Injection
Injection of triamcinolone administered as an adjuvant following pulsed radiofrequency of the dorsal root ganglion.
Locations (1)
RSUD Tarakan
Jakarta, DKI Jakarta, Indonesia