Clinical Research Directory

Inclusion Criteria: * Adults aged 18 through 90 years at enrollment. * Able to provide informed consent, or have a legally authorized representative provide consent when permitted by the applicable protocol and regulations. * Able and willing to participate in prospective longitudinal digital biomarker monitoring. * Able to use, or permit application of, study-authorized wearable or remote-monitoring technologies. * Able and willing to provide protocol-specified physiologic, behavioral, acoustic, and symptom data. * Expected to have sufficient follow-up to permit evaluation of the 72-hour prediction endpoint. * Willing to comply with study procedures and data-collection requirements. Exclusion Criteria: * Inability to provide informed consent or otherwise participate through an approved consent process. * Clinical or technical circumstances that prevent reliable collection of the required multimodal digital biomarker data. * Inability or unwillingness to comply with study monitoring procedures. * Enrollment in another study that, in the investigator's judgment, would materially interfere with FUSION-72 data collection or endpoint assessment. * Any circumstance that, in the investigator's judgment, would make participation inappropriate or compromise the integrity of the study.