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Children in Cardiac Intensive Care Requiring Surgery for Congenital Heart Disease

Tundra lists 1 Children in Cardiac Intensive Care Requiring Surgery for Congenital Heart Disease clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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NOT YET RECRUITING

NCT07327502

Antibiotics Distribution Study in Peripheral Compartments: Contribution of Microdialysis

Postoperative mediastinitis is an important cause of postoperative morbidity in children. The main objective of this study is to describe the distribution of cefazolin, using as surgical antibiotic prophylaxis, in the mediastinal compartment in children after cardiac surgery for congenital heart disease. The investigators aims to build a population pharmacokinetic model of cefazolin using plasma and tissue concentrations in order to optimize and individualize cefazolin dosing regimens. Cefazolin tissue pharmacokinetics will use a microdialysis procedure.

Gender: All

Ages: 6 Months - 6 Years

Updated: 2026-01-08

1 state

Children in Cardiac Intensive Care Requiring Surgery for Congenital Heart Disease