Clinical Research Directory

Neuroscience-Based Exercise Training in Female Volleyball Players

24 volunteer professional female volleyball players (aged 16-21), licensed in the Turkish Volleyball Federation (TVF) Women's Volleyball League 2 and 3, will be included in the study. Participants will be randomized into intervention (n=12) and control (n=12) groups using www.randomizer.org. The intervention group will receive an 8-week (3 days/week) neuro-athletic exercise training program, including eye warm-up exercises and volleyball-specific visual and motor coordination stations, in addition to their regular training. The control group will continue with regular training only. Both groups will have equal total training time. Visual attention and decision-making strategies will be measured with a wearable eye-tracking system (Pupil Labs Invisible) during a serve task. Cortical activation (oxygenated and deoxygenated hemoglobin levels) in the frontal cortex during the same serve task will be measured simultaneously with functional near-infrared spectroscopy (fNIRS). Sport-specific physical fitness will be evaluated with the T-Agility Test, radar gun serve speed measurement, VERT wearable jump analysis system, Y-Balance Test, and sit-and-reach test. All assessments will be conducted before training begins and after the 8-week program. The study aims to determine whether neuro-athletic exercise training improves cortical activation, visual attention, decision-making processes, and sport-specific physical fitness parameters in professional female volleyball players, compared to a control group receiving regular training only.

Menstrual Cycle TMS Plasticity Pilot

Aim 1: Assess how menstrual cycle phase affects motor cortex plasticity in females. Aim 2: Compare motor cortex plasticity between males and females across the same time points, identifying potential sex differences in TMS response. Aim 3: Examine associations between serum hormone levels and TMS-induced plasticity within and between sexes.

LAnguage-Motor Imagery Circuits to Improve Motor Learning and Language Comprehension

Recent evidence suggests that cognitive systems do not operate in isolation but interact within broader networks, thus opening new avenues for fundamental and clinical research. An illustrative example is the interaction between language comprehension and motor representations. For instance, motor training (e.g., sports, origami training) can facilitate action verb recognition, whereas motor deficits (e.g., upper limb immobilization) can hinder the processing of action language. Similarly, action language has been shown to affect motor performance. These effects are attributed to an implicit form of motor imagery, an automatic simulation of motor experience (without actual movement) evoked by action words. Interestingly, literature supports the idea that the motor simulations used for imagining an action are also engaged during the reading of action language, leading to similar neurophysiological and behavioral changes in both processes. However, questions remain about the similarity of the simulations generated by motor imagery and action language. This project, encompassing three experimental sequences, aims to address these questions to achieve significant scientific advancements in both theoretical and applied domains.