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Clinical Research Directory

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4 clinical studies listed.

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Injection Site Pain

Tundra lists 4 Injection Site Pain clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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COMPLETED

NCT07860099

The Effect of the Cold Needle Technique on Pain and Patient Satisfaction Levels During Intramuscular Injection Administered to the Ventrogluteal Site

This randomized controlled trial aims to evaluate the effect of the cold needle technique on pain and patient satisfaction during intramuscular injections administered to the ventrogluteal site. The study was conducted in the internal medicine clinics of Prof. Dr. Cemil Taşçıoğlu City Hospital in Istanbul, Türkiye. A total of 78 adult patients receiving intramuscular vitamin B12 injections as part of their prescribed treatment participated in the study. Participants were randomly assigned to an intervention group (n=40) or a control group (n=38). The intervention group received intramuscular injections using a cooled needle, while the control group received injections using the standard technique. Only the injection needle was cooled; the medication was not cooled. Pain intensity and patient satisfaction were assessed after the injection using Visual Analog Scales (VAS). The study aims to determine whether the cold needle technique reduces injection-related pain and improves patient satisfaction compared with the standard intramuscular injection technique.

Gender: All

Ages: 18 Years - Any

Updated: 2026-10-06

1 state

Injection Site Pain
COMPLETED

NCT07820956

Ice Application for Oxacillin-Related Phlebitis and Pain

This randomized controlled trial evaluated whether ice application could reduce pain and peripheral intravenous phlebitis associated with oxacillin administration. Hospitalized patients receiving intravenous oxacillin were assigned to either an ice application group or a control group. In the intervention group, ice was applied to the area around the peripheral intravenous catheter before oxacillin administration. In the control group, a room-temperature water bag was applied in the same manner. Pain after oxacillin administration and signs of phlebitis at the intravenous catheter site were assessed and compared between the two groups. The study aimed to determine whether ice application could provide a simple, non-pharmacological approach to reducing oxacillin-related pain and phlebitis.

Gender: All

Ages: 20 Years - 60 Years

Updated: 2026-09-15

Peripheral Intravenous Phlebitis
Injection Site Pain
Pain
COMPLETED

NCT07703553

Comparing Pre-Anesthetic Approaches in Dentistry

The main purpose of this study is to find out which pre-treatment method works best to reduce pain from dental anesthesia injections in adult patients. Researchers will compare four different approaches: Topical numbing spray (10% lidocaine) Brief cold application (cryotherapy) A combination of both cold application and cooled numbing spray A control group Participants who need a standard local anesthesia injection for their dental treatment will be randomly assigned to one of these four groups. Right after the needle insertion, participants will rate their pain level using a simple visual scale, and their physical reactions will also be observed and scored by the researchers.

Gender: All

Ages: 18 Years - 65 Years

Updated: 2026-09-10

1 state

Injection Site Pain
Pain
RECRUITING

NCT07004166

Effects of TPR and Z Techniques on Pain and Drug Leakage in Intramuscular Injections

This randomized, triple-blind clinical trial compares the effectiveness of Z-track and TPR (traction-pressure-release) techniques in reducing pain and medication leakage during ventrogluteal intramuscular injections. Pain is measured using VAS, and leakage is assessed with a millimeter scale. The study aims to identify a more efficient, less painful injection method.

Gender: All

Ages: 18 Years - 40 Years

Updated: 2025-06-04

Muscle Pain
Injection Site Pain