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2 clinical studies listed.
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Tundra lists 2 Materials Testing clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.
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NCT02874625
RCT to Evaluate Biocompatibility of Resin-based Dental Materials
In this randomized clinical trial, the bio-compatibility of 2 materials used for dental restorations will be compared: glass-ionomer vs resin-based composites. Urine and saliva samples will be taken for determination of bisphenol A levels at several time points, and for analysis of the estrogenic activity using ERE-CALUX. Also buccal cells will be taken. Next, DNA extraction will be done with a commercial kit. Global alterations in DNA methylation and DNA hydroxymethylation levels will be determined using UPLC-MS/MS.
Gender: All
Ages: 4 Years - 10 Years
Updated: 2024-07-03
NCT02874599
Cohort Biomonitoring Study to Evaluate the Biocompatibilty of Resin-based Dental Materials
Adult patients who require multiple dental restorations will be included in this study. Urine and saliva samples will be taken for determination of bisphenol A levels at several time points, and for analysis of the estrogenic activity using ERE-CALUX. Also buccal cells will be taken. Next, DNA extraction will be done with a commercial kit. We will determine global alterations in DNA methylation and DNA hydroxymethylation levels using UPLC-MS/MS.
Gender: All
Ages: 18 Years - Any
Updated: 2024-07-03