Clinical Research Directory

Real-Time Monitoring of the Injection Pressure During the Peripheral Nerve Block

The goal of this clinical trial with medical device is to learn if the Smart Needle Monitoring System works to maintain a safe low injection pressure during a type of regional anaesthetic (Peripheral Nerve Block (PNB)) in patients due to undergo surgery below the elbow . It will also learn about the safety of the device and patients' perception of the quality of anesthesia. Participants will: * be operated locally according to standard clinical practice * undergo post-anesthesia recovery and any neurologic symptoms or signs assessment on postoperative days 1 and 7

Stable Versus Unstable Resistance Training Effects on Physical Fitness and Physiological Biomarkers of Untrained Male University Students

The goal of this clinical trial is to learn the effects of stable and unstable resistance training on physical fitness, kidney function and blood lipid tests in healthy young male volunteers. The main questions it aims to answer are: * Do both stable and unstable resistance training increase the level of urinary protein clearance greater than the control group? * What is the difference in improvement of lipid profiles among the groups? * Does unstable resistance training mode rise muscular endurance greater than stable resistance training? Researchers will compare stable and unstable resistance training to see if there are differences on physical fitness measures, blood lipid and urinary protein tests. Participants, in their respective group will receive ten weeks of: * Stable resistance training * Unstable resistance training or * No exercise training intervention

Fast vs. Slow Pranayama for Breathing, Heart, Balance, and Well-Being in Students

The goal of this clinical trial is to compare the effects of slow and rapid pranayama techniques on respiratory, cardiovascular, balance, and psychosocial parameters in healthy adults aged 18-35 years. The main questions it aims to answer are: Do slow and rapid pranayama techniques produce different improvements in lung volumes and peak cough flow? Does slow pranayama lead to greater improvements in oxygen saturation and cardiovascular parameters, while rapid pranayama provides greater gains in balance and respiratory flow values? Researchers will compare a slow pranayama group (n = 39) and a rapid pranayama group (n = 39) to determine how breathing speed influences physiological and psychosocial outcomes. Participants will: Be randomly assigned to one of two groups (slow or rapid pranayama). Practice their assigned pranayama techniques for 25-30 minutes, 4 days per week for 12 weeks (one supervised, three home-based sessions). Undergo pre- and post-intervention assessments including spirometry (FVC, FEV₁, FEF25%-75%, PEF), oxygen saturation, peak cough flow, blood pressure, heart rate, balance tests (single-leg stance, Y-Balance Test), and validated questionnaires for perceived stress, anxiety, depression, fatigue, and sleep quality. This study aims to clarify how controlled breathing speed influences respiratory efficiency, cardiovascular regulation, postural stability, and mental well-being in young adults, contributing to evidence-based recommendations for integrating pranayama into stress-management and preventive rehabilitation programs.

Carotenoids in the Skin and Immune Aging

This study aims to examine the connection between the level of carotenoids in the skin and a number of immune related health parameters.

Novel Multimodal Neural, Physiological, and Behavioral Sensing and Machine Learning for Mental States

In this program, the investigators will develop novel multimodal neural-behavioral-physiological monitoring tools (software and hardware), and machine learning models for mental states within social processes and beyond. The tools consist of a multimodal skin-like wearable sensor for physiological and biochemical sensing; a conversational virtual human platform to evoke naturalistic social processes; audiovisual affect recognition software; synchronization tools; and machine learning methods to model the multimodal data. The investigators will demonstrate the tools in healthy subjects without neural recordings and in patients with drug-resistant epilepsy who already have intracranial EEG (iEEG) electrodes implanted based on clinical criteria for standard monitoring to localize seizures, which is unrelated to our study.

CLAiR Pivotal Study

This is a multi-site, observational clinical study to validate the performance of the CLAiR AI software in identifying elevated atherosclerotic cardiovascular disease (ASCVD) risk from retinal (eye) images obtained from two different retinal image camera models.

Protein Source and Resistance Training

The goal of this clinical trial is to investigate the role of whole food protein source compared with supplement forms in enhancing response to resistance exercise training in moderately active participants. The main question it aims to answer: Whether wholefood protein (lean red meat) consumption is equivalent to supplementation in supporting muscle function and composition responses to resistance training? Whether wholefood protein consumption results in additional benefits to micronutrient status above that of supplementations? Researchers will compare both lean red meat and whey protein groups with an isocaloric maltodextrin control to see if protein intake enhanced response to resistance training. * Participants will be randomized to consume one of three treatments: (1) lean red meat, (2) a whey protein supplement, or (3) an isocaloric maltodextrin control beverage following each resistance training session. * Participants will complete a 12-week progressive resistance training programme consisting of 3 exercise sessions per week. * Participants will undergo skeletal muscle performance testing by way of Vertical jump height, isokinetic strength tests and estimated one repetition maximum tests prior to and following the 12-week resistance training programme. * Participants will undergo body composition assessment by way of bioelectrical impedance analysis, thigh muscle ultrasound and skinfold measurement prior to and following the 12-week resistance training programme.

NutFinForce: The Impact of Digitally Delivered Lifestyle Performance Medicine Intervention on Defense Performance in Finland

Summaries are in Finnish for attendees are availabe and reviewed in ethical approcval process