Clinical Research Directory

Process of Emergence and Implementation of Advanced Practice Nursing in France

Longitudinal, observational research with a mixed quantitative (by questionnaires) and qualitative (by interviews and observations) approach, multidisciplinary, among Advanced Practice Nurses (APNs) already graduated and 3 consecutive classes of advanced practice students who will be followed annually during their implementation as APN until the last year of the study. The questionnaires will focus on APN scope of practice evolution, economical analysis and geographical distribution of APN. The ethnographical approach will assess APN settlements and relation with healthcare colleagues and patients.

Does Longitudinal Nursing Follow-up Improve Smoking Cessation in Patients Referred for COPD Screening

a monocentric study to evaluate the efficacy of a longitudinal nursing follow up in smoking cessation in patients screened for Chronic obstructive pulmonary disease (COPD).

Effect of Virtual Reality on Pain and Anxiety During Pap Smear Testing

This randomized controlled pretest-posttest experimental study aims to evaluate the effect of virtual reality (VR) on pain and anxiety levels experienced during Pap smear sampling. Although cervical cancer is largely preventable through regular screening, many women avoid Pap smear testing due to anxiety, fear of pain, and discomfort during gynecological examinations. Innovative, non-invasive interventions are needed to improve women's screening experiences and participation rates. The study will be conducted in a gynecology outpatient clinic with 60 women aged 18-65 years who meet the inclusion criteria and provide informed consent. Participants will be randomly assigned to either the intervention group (VR headset during the procedure) or the control group (standard care). Women in the intervention group will watch a 360° relaxing nature video during the Pap smear procedure. Data will be collected using a Personal Information Form, the State Anxiety Inventory, and the Visual Analog Scale (VAS). The findings may support integrating VR into clinical practice to enhance patient comfort during screening procedures.

Effect of Standardized Patient Simulation on Nursing Students' Assessment, Diagnosis Skills, and Experiences

This randomized controlled study aims to determine the effect of teaching delivered through standardized patient simulation on nursing students' assessment and nursing diagnosis determination skills, as well as their learning experiences. First-year nursing students will be randomly assigned to intervention and control groups. The intervention group will receive training based on standardized patient simulation, while the control group will receive traditional instruction. Data will be collected using a sociodemographic information form, case-based assessment tools, and measurement instruments designed to evaluate students' perceptions and experiences related to the educational process. Group comparisons will be conducted to evaluate the effectiveness of the simulation-based teaching method.

EVIDENCE-BASED NURSING CARE AMONG SURGICAL NURSES

Background: There is a limited number of studies in Turkey that jointly evaluate the evidence-based practice levels of nurses working in surgical units, the barriers they encounter in practice, and the facilitating factors that support practice. In particular, understanding the extent to which evidence-based nursing practice beliefs predict evidence-based care practice behaviors is important for designing in-house training programs, creating clinical guidelines, and developing in-service mentoring systems. Purpose: This research was conducted to reveal the levels of evidence-based nursing practice among nurses working in surgical units, identify barriers to implementation, and define factors that facilitate implementation. It is anticipated that the findings will guide clinical managers, education planners, and policy developers in creating evidence-based improvement strategies. Methodology: The research is a descriptive-cross-sectional study. The population consists of nurses working in the Surgical Clinics at Uludağ University Faculty of Medicine Hospital in Bursa, Turkey (N:350). The sample calculation for the study was performed using the known population sample method. The minimum number of individuals required in the sample was calculated using the Raosoft sample calculation tool, yielding a sample size (n) of 184 when a 5% margin of error and a 95% confidence interval were applied.

Evaluation of the Integrated Smart Pump-EHR Technology in Eight Adult Acute and Intensive Care Units

This study looks at the effects of using "smart pumps" that connect with the Electronic Health Record (EHR) in 8 adult ICU units. We will interview nurses and healthcare team members to learn about any challenges with this technology. All nurses in these units will be invited to complete a survey on how easy the technology is to use. Some nurses will practice giving medications to "mannequins" in a simulation lab to see how they work with the pumps. We will also look at existing data to find out how many nurses use the technology and what types of alerts or errors come up. Finally, we will review patient charts to see if using the technology has increased or decreased errors in recording IV medication amounts.

The Role of Mandala Painting Before Surgery

Surgical interventions often cause significant anxiety and stress in patients during the preoperative period. In this study, it is aimed to determine the effect of mandala coloring, a non-pharmacological and art-based intervention, on reducing anxiety and stress levels in individuals scheduled for elective surgery. The universe of the study will consist of patients who will undergo elective surgery between June 2025 and June 2026 in the General Surgery Clinic of Istanbul Sultangazi Training and Research Hospital. Data will be collected using the Introductory Information Form, State Anxiety Inventory (STAI-S), Perceived Stress Scale (PSS), and Physiological Parameters Form (including blood pressure, pulse, respiration rate, and oxygen saturation). One day before surgery, patients who meet the inclusion criteria will be informed about the study and randomized into intervention and control groups using a random number table created with MS Excel software. Patients in the intervention group will perform a 20-minute mandala coloring activity in the preoperative waiting period. Before and after the application, participants' anxiety and stress levels will be evaluated with the STAI-S and PSS, and their physiological parameters will be recorded. Patients in the control group will receive standard preoperative care and will be evaluated at the same time points with the same tools, without any intervention. The study aims to provide evidence for the use of mandala coloring as a simple, low-cost, and effective nursing intervention to reduce preoperative anxiety and stress.

The Effect of Ney Music on Patients Undergoing Lumbar Disc Surgery

This randomized controlled study aims to investigate the effects of ney music listening, a traditional Turkish wind instrument, on pain, anxiety, sleep quality, and vital signs in patients undergoing lumbar disc herniation surgery. Participants will be randomly assigned to intervention and control groups. The intervention group will receive a 15-minute ney music session at three different time points: preoperative (on the day of surgery), postoperative 3rd hour, and postoperative day 1. The control group will receive standard postoperative nursing care without music intervention. Data will be collected at the same time points in both groups using the Visual Analog Scale (VAS), State-Trait Anxiety Inventory (STAI-I), Richard-Campbell Sleep Questionnaire, and vital signs. The study seeks to evaluate the non-pharmacological benefits of therapeutic music in postoperative recovery.

Remote Monitoring After Heart Failure

Heart failure (HF) is a leading cause of hospitalisation and disability-adjusted life years lost, with mortality rates exceeding most cancers. Despite compelling evidence and recommendations, less than 20% of the HF patients are followed-up by the specialist healthcare after hospital discharge. Due to limited outpatient capacity, human resources and increasing incidence of HF over the next decades, new care models are obviously needed. Remote monitoring (i.e. telemonitoring) encompasses the use of audio, video and other telecommunication technologies to monitor patient status at a distance. Remote monitoring is a promising strategy that can facilitate rapid access to care when needed and reduce patient travel to hospital consultations. It also promotes self-care behaviour, psychosocial support, and early detection of cardiac decompensation. Despite intensive research for \>10 years, randomised trials show conflicting results, and European HF guidelines are confined to a weak (class IIb, level of evidence B) recommendation. More knowledge about the role of remote monitoring strategies in HF management, especially in the transition from hospital to home, is thus requested in the most recent European and US guidelines. In particular, studies of high-risk patients integrating the community health services are largely lacking. Furthermore, the components of the intervention that mediate the effect need to be identified. The proposed study aims to address these gaps in evidence and assess whether individually tailored remote monitoring at home (IT-HEART) is improves clinical outcomes in patients hospitalized with decompensated HF. We also aim to identify modifiable clinical and behavioural (drug adherence, self-care, psychological factors) outcome predictors. A prospective, multicentre, randomized, open-label, blinded endpoint adjudication (PROBE) intervention study is designed and powered to include at least 200 patients with at least one HF hospitalization in the 12 months preceding enrolment. To ensure generalizability, patients will be included regardless of comorbidity, frailty and ejection fraction. We have conducted a pilot-study providing empirical evidence for the expected participation rate, readmission rate and barriers to HF management in current clinical practice that will be targets for the intervention. This will promote high adherence to the intervention and positive long-term clinical and health economic effects.

Advancing Nursing Practices in Hospital Oncology Care

The purpose of this study is to find out if a new training program for nurses called PACT (Partnership, Assessment, Care, and Transition) will be effective and relevant in helping nurses gain the skills needed to provide high-quality family-centered care. Family-centered care skills include engaging family caregivers as partners in patient care, and strengthening their capacity for caregiving by assessing family support needs and facilitating access to resources when needed. The study will also look at whether the quality of nurses' family-centered care skills is associated with improved outcomes for family caregivers. Both nurses and family caregivers will be enrolled in this study. Participants will be nurses/caregivers who care for advanced GI cancer patients admitted to Memorial Sloan Kettering.

The Effect of Baduanjin on Patients Undergoing Knee Replacement Surgery

This randomized controlled trial aims to evaluate the effects of Baduanjin, a traditional Chinese mind-body exercise, on pain, comfort, and quality of recovery in patients undergoing total knee arthroplasty (TKA). The study will be conducted between July 2025 and July 2026 at Yalova Training and Research Hospital's Orthopedics Clinic. Sixty patients will be randomly assigned into two groups: an intervention group practicing Baduanjin and a control group receiving standard postoperative care. The intervention will begin on the first postoperative day and continue for three weeks. Outcome measures include the Visual Analog Scale (VAS) for pain, the General Comfort Questionnaire, and the Quality of Recovery-40 (QoR-40) questionnaire. These assessments will be conducted weekly for three weeks. The control group will follow routine postoperative care without Baduanjin. The primary objective is to determine whether Baduanjin can improve postoperative outcomes in terms of pain reduction, increased comfort, and better recovery quality.

ABCDEF Bundle to Prevent Delirium for COPD Patients

Abstract Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory disorder characterized by persistent airflow limitation and chronic respiratory symptoms, resulting from abnormalities in the bronchi, bronchioles, and alveoli. Patients with COPD may require admission to intensive care units (ICUs), particularly during acute exacerbations. In this context, both disease management and the prevention of potential complications, such as delirium, are of critical importance. Delirium is a common, preventable, and serious complication in ICUs that prolongs hospital stays, increases healthcare costs, and heightens the risk of infections. Hypoxia-induced cognitive impairment is among the key contributing factors to delirium in patients with COPD. To improve patient outcomes, the ABCDEF Care Bundle was introduced in 2013 as a structured and evidence-based approach to ICU care. This study aims to evaluate the effectiveness of the ABCDEF Care Bundle in preventing delirium in patients with COPD admitted to the ICU. The research will be conducted as a randomized controlled trial between April and December 2025 in the third-level ICU of Taksim Training and Research Hospital. The study population will consist of COPD patients, with a total sample size of 84 patients (42 in each group), randomly assigned using a computer-assisted simple randomization method. A variety of validated instruments will be used to assess pain, sedation, cognitive status, mobility, and sleep quality. The findings of this study are expected to contribute to the growing body of evidence supporting structured ICU care and to raise awareness among healthcare professionals regarding the implementation of the ABCDEF Care Bundle. Keywords: ABCDEF Care Bundle, Delirium, COPD, Intensive Care, Nursing Care, Randomized Controlled Trial

Nursing Students Education Virtual Reality Wound Care

This study is a randomized controlled trial aiming to determine the effect of pressure sore prevention education given to nursing students at a foundation university through virtual reality on student satisfaction, self-confidence perception and knowledge retention. The study will investigate whether virtual reality training affects student satisfaction and self-directed learning skills, differences between pre-test and post-test scores, and retention of the training. 66 nursing students will be included in the study, the experimental group will be trained with VR goggles and the control group will be provided with written material. The data obtained during the data collection process will be analyzed with the SPSS V23.0 program, descriptive statistics and appropriate parametric or nonparametric tests will be used. The measurement tools to be used include the 20-question "Knowledge Assessment Form for Pressure Ulcer Prevention" developed by Jeffries \& Rizzolo and the "Student Satisfaction and Self-Confidence in Learning Scale". Ethics committee approval, relevant permissions and participant consent will be obtained for the study and the data obtained will be stored for 5 years and then destroyed. The literature review reveals the widespread use of virtual reality in education, healthcare and other fields and the critical role of pressure sore prevention in reducing healthcare costs and improving the quality of patient care.

The Effect of Breastfeeding Counseling on Social Support Perception, Breastfeeding Self-Efficacy and Outcomes

The purpose of this study is to examine the effects of the Breastfeeding Self-Efficacy Resources Development Nurse Consultancy Program (EMÖZGEDAP), based on Dennis's Breastfeeding Self-Efficacy Theory along with the hypno-breastfeeding philosophy given to mothers and family relatives, on social support perception, breastfeeding self-efficacy and outcomes. The study will involve pregnant women and close others assigned randomly to the intervention (n=50) or control (n=50) groups in a state hospital in Turkey. Individual counseling will be provided to the intervention group within the scope of the EMÖZGEDAP, based on Denis's Breastfeeding Self-Efficacy theory and hypnobreastfeeding philosophy. EMÖZGEDAP, which will be applied to pregnant women and their family relatives, will consist of 5 sessions lasting 7.5 hours (2 sessions with the woman and her family relatives, two sessions with the woman alone, and one with her family relatives alone). The Antenatal Breastfeeding Self-Efficacy Scale will be evaluated before the counseling program is given in the antepartum period. Breastfeeding and Nutrition Results, Postpartum Breastfeeding Self-Efficacy Scale, Breastfeeding Self-Efficacy Scale for Fathers, Assessment Scale for Perceived Support of Close Others in Relation to Breastfeeding Self-Efficacy and Scale of Perception of Close Others' Support For Breastfeeding Self-Efficacy will be evaluated at the 1st, 3rd, and 6th months postpartum.

Perceptions of Student Nurses About Professional Nursing Values of Creative Drama Education

Objective: This study will be carried out as a pre-test-post-test randomised controlled study to examine the effect of creative drama training on the perception of professional values in nursing students. Materials and Methods: In the study, it was planned to collect data using Personal Information Form and Professional Values of Nurses Scale (HPVS) as data collection tools. SPSS 25.0 (Statistical Package for Social Science) programme will be used for data analysis. Design: Randomised controlled. Study Group: The study was planned to be conducted with student nurses studying at Istanbul Arel University, Faculty of Health Sciences, Department of Nursing. The sample size of the study was calculated as a minimum of 68, 34 in the experimental group and 34 in the control group, based on Cohen's standardised effect size of 0.80 and with a power of 0.90 with the 'G. Power-3.1.9.4' programme.

Flipped Learning Model on Nursing Students' Thorax and Heart Examination

This study is planned to determine the impact of education provided with the flipped learning model on nursing students' thorax and heart knowledge and self-directed learning skills. This study adopted a pretest-posttest openlabel randomized controlled trial. The population of the study will consist of second-year students studying at a Nursing Department of a university in Turkey during the 2023-2024 academic year.According to the power analysis, it was determined that the study needs to be conducted with a total of 100 students, with 50 students in the experimental group and 50 students in the control group.The experimental group participants were trained using the flipped learning model.For the control group, the topic will be delivered using only traditional teaching methods.The data for the study will be collected using the "Introductory Characteristics Form," the "Thoracic and Cardiac Examination Information Evaluation Form," and the "Self-Regulated Learning Skills Scale (SRLSS)."The collected data will be analyzed using SPSS 15 software.

Virtual Game Simulation in Patient Safety

With the development of technology, virtual game simulation is starting to take an important place in nursing education, which has spread to the virtual world. There are studies conducted with this application, but there are no virtual game simulation studies related to patient safety. The planned study aims to measure nursing students' tendencies and attitudes towards medical errors, satisfaction and self-confidence in nursing practices with a virtual game simulation related to patient safety developed by the researcher.

Educational Intervention and Adherence

quasi-experimental, parallel study, with the objective of evaluating the effectiveness of an educational nursing intervention supported by ICTs, for the improvement of therapeutic adherence in people undergoing hemodialysis treatment in a renal unit in Barranquilla (Colombia)

The Effect of Kangaroo Father Care Transport on Preterm Infants

This study was planned to investigate the effect of paternal kangaroo care and transport on physiologic parameters, anxiety and paternal attachment in preterm infants.

Laughter Yoga Effect on Cancer Patients' Physiopsychological Symptoms

The universe of this study will consist of cancer patients and their relatives who are hospitalized in the medical oncology clinic of Atatürk University Research and Practice Hospital between Oct 2024 and Feb 2024. The researcher will stratify the patients in the control and intervention groups according to age and the type of treatment they receive in order to ensure homogeneity. Accordingly, the patient in each stratum will be selected from one of the labels prepared in a bag with the words "experimental" and "control" written on it and the patient will be included in the group written on the label. The patients in the control and intervention groups will not know which group they are in, but only the researcher will know who is in which group. In this way, blinding will be ensured and the study will be completed as single-blind.

Nurse Implemented Infant-Mother Attachment Security Program

This study focuses on adapting and evaluating an attachment-based intervention program implemented by nurses in Family Health Centers (FHCs) in Turkey. The program aims to enhance parental sensitivity and infant-mother attachment security. Evidence suggests that such programs, developed in Western countries, effectively improve parenting behaviors and attachment quality. Despite the positive effects of similar programs in Turkey, their integration into primary healthcare for wider public benefit remains unexplored. The project will develop an intervention protocol based on effective methods from previous attachment-based programs into routine childcare visits at FHCs. A randomized controlled trial involving 120 mothers with 9- to 12-month-old babies in Istanbul will be recruited. FHCs will be randomly assigned to intervention and control groups, with 60 mother-infant dyads in each condition. Nurses will deliver the program during childcare visits at 9, 12, 15, and 18 months. Intervention FHCs will also use reminders like posters and short films in the waiting rooms to reinforce the concepts. Effectiveness will be evaluated through pretest, posttest, and follow-up home visits using observational and self-report measures on attachment security, maternal sensitivity, as well as maternal psychological characteristics, along with infant socioemotional measures. Upon completion of the project, control FHC nurses will receive training to deliver a condensed version of the program.

Video-Assisted Self-Assessment on Nasogastric Tube Insertion

Introduction and Purpose Advancements in Nursing Education: The integration of technology, specifically video-supported training, is a significant development in nursing education. Focus on Nasogastric Tube (NGT) Placement: Proper placement of NGT is a critical skill in nursing. Traditional methods alone may not suffice in acquiring and maintaining this skill. Objective: Evaluate the impact of video-supported self-assessment on the knowledge and skills of nursing students regarding NGT placement. Hypotheses Video-supported self-assessment increases students' knowledge about NGT placement. Video-supported self-assessment enhances students' skills in NGT placement. Materials and Methods Design: A randomized controlled pre-test and post-test experimental design. Ethics: Ethical approval will be obtained and registered with Clinical Trials ID. Data Collection Tools: FR.1 Personal Information Form: Demographic data collection. FR.2 NGT Placement Knowledge Test: 20 multiple-choice questions based on theoretical content. FR.3 NGT Placement Skill Checklist: 51 steps evaluating correct, incorrect, and unobserved applications. Data Collection Process Initial Phase: Explanation of the study, informed consent, and completion of the FR.1 form and FR.2 pre-test. Traditional Teaching: A theoretical lecture on NGT placement. Practical Application: Experimental Group: Practical demonstration recorded and shared with students for self-assessment. Control Group: Practical demonstration recorded but not shared with students. Post-Intervention Assessment: FR.2 post-test and an OSCE exam based on FR.3 for both groups after one week. Data Analysis Software: SPSS 23.0. Methods: T-tests, Chi-square tests, Pearson and Spearman correlation analyses depending on data distribution. Statistical Significance: p\<0.05. Study Limitations Scope: Limited to first-year nursing students at one university. Interaction: Potential interaction between intervention and control group students. Ethical Principles Approval: Obtained from the Ethics Committee and the university. Participant Rights: Informed consent, respect for autonomy, confidentiality, and adherence to the Helsinki Declaration. This summary captures the essence of the research study described in the original document, focusing on the purpose, methods, data collection, analysis, limitations, and ethical considerations.

Effectiveness of Massage Applied to Hemodialysis Patients

This study was conducted to determine the effect of massage on comfort and fatigue levels of hemodialysis patients.

Digital Navigators for Acceptance and Competence Development with Mental Health Apps

The goal of this clinical trial is to learn if and how so called "Digital Navigators" (DN) can help general practitioners, outpatient psychiatrists and psychologists as well as their treated patients to use digital mental health apps (DiGAs) and integrate it into their treatment. The main questions it aims to answer are: * What are the chances and implementation barriers of DN? * What are the acceptance and expectations towards DN? * Do DN affect the psychological health of patients? * Do DN affect the digital health literacy and technical competence of participants? Employees of medical teams (e.g. medical assistants) receive training to become a DN. Afterwards patients are accompanied and supported by the DN for 12 weeks to select and use a suitable app for their mental disorder.