Clinical Research Directory

Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric AKI

This study follows a group of patients admitted to the PICU who are identified as being at risk for developing acute kidney injury. The investigators will use risk-stratification, biomarker testing, and a functional assessment to predict patients who will become fluid overloaded and develop acute kidney injury.

Therapeutic Robots for Alleviating ICU Stress in Children

The purpose of this study is: (a) to examine the changes in anxiety, depression symptoms, and positive/negative emotions before and after the intervention, as well as before discharge from the intensive care unit (ICU) in the experimental group (using the therapeutic robot PARO), the control group (using a stuffed seal), and the comparison group (receiving standard care). (b) To compare the effectiveness in relieving anxiety, depression symptoms, and positive/negative emotions among the experimental group, control group, and comparison group for ICU pediatric and adolescent patients in the school-age period. The research questions addressed in this study are: 1. What are the changes in anxiety, depression symptoms, and negative emotions before and after the intervention in the experimental group? 2. What are the changes in anxiety, depression symptoms, and negative emotions before and after the intervention in the control group? 3. What are the changes in anxiety, depression symptoms, and negative emotions before and after the intervention in the comparison group? 4. What is the effectiveness in reducing anxiety after the intervention among the experimental group, control group, and comparison group? 5. What is the effectiveness in alleviating depression symptoms after the intervention among the experimental group, control group, and comparison group? 6. What is the effectiveness in reducing negative emotions and increasing positive emotions after the intervention among the experimental group, control group, and comparison group?

Advanced Dressings for CVC Infection Prevention in PICU

Randomised, single-blind clinical trial comparing chlorhexidine gluconate-impregnated transparent dressings versus conventional transparent dressings in the prevention of central venous catheter-related bloodstream infections (CVC-BSI) in paediatric patients admitted to a tertiary hospital PICU. Outcomes include incidence of BRCVC, catheter colonisation, dressing-related skin complications, and number of dressing changes.

Nutritional Status of Critically Ill Children in Pediatric Intensive Care Units at Sohag University Hospitals

The goal of this observational study is to evaluate nutritional status of critically ill patients admitted to Pediatric Intensive Care Units (PICU) at Sohag University Hospital and its correlation with their outcome as regarding to need for mechanical ventilation, acquired infection, metabolic complications, and mortality.