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Piriformis Syndrome

Tundra lists 16 Piriformis Syndrome clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ENROLLING BY INVITATION

NCT07502573

Telerehabilitation vs. Home Exercise in Piriformis Syndrome: A Comparative Study

The aim of this study is to compare the effects of asynchronous telerehabilitation and home exercise programs on pain, fear of pain, functionality, and performance in individuals with piriformis syndrome.

Gender: All

Ages: 18 Years - 45 Years

Updated: 2026-03-31

1 state

Piriformis Syndrome
Exercise Training
Telerehabilitation
NOT YET RECRUITING

NCT07473349

Diagnostic Accuracy of Clinical Tests and Diagnostic Criteria for Piriformis Syndrome

Piriformis syndrome is a clinical condition characterized by buttock pain and/or sciatic-like symptoms, and its diagnosis remains challenging because there is no universally accepted diagnostic standard. This study aims to evaluate the diagnostic accuracy of commonly used diagnostic criteria and clinical tests for piriformis syndrome. Participants with suspected piriformis syndrome will undergo standardized physical examination and assessment of predefined diagnostic criteria. Ultrasound-guided injection of 5 mL of 2% lidocaine into the piriformis muscle will be used as the reference diagnostic procedure. A reduction of 50% or more in pain after injection will be considered confirmation of piriformis syndrome. The diagnostic performance of clinical tests and diagnostic criteria will be analyzed accordingly.

Gender: All

Ages: 18 Years - 75 Years

Updated: 2026-03-17

Piriformis Syndrome
Gluteal Pain
NOT YET RECRUITING

NCT07326982

Ultrasound-Guided Interfascial Hydrodissection for Gluteal Myofascial Pain in Piriformis Syndrome: A Prospective Study

This randomized, double-blind prospective trial investigates whether ultrasound-guided interfascial hydrodissection using 10% dextrose is more effective than dry needling in treating gluteal myofascial pain coexisting with piriformis syndrome. Following diagnostic piriformis injection response, eligible patients will be randomized into two treatment arms and followed at 1 hour, 1 week, 1 month, and 3 months. The primary hypothesis is that interfascial hydrodissection will provide superior long-term analgesic outcomes due to fascial separation, neuromodulation, and nociceptor suppression.

Gender: All

Ages: 18 Years - 75 Years

Updated: 2026-03-13

1 state

Piriformis Syndrome
Gluteus Maximus Myofascial Pain
ENROLLING BY INVITATION

NCT07322185

Comparative Effects of Stecco-fascial Manipulation and Rolfing Structural Integration in Patients With Piriformis Syndrome

This study aims to compare the effectiveness of Stecco Fascial Manipulation and Rolfing Structural Integration in treating Piriformis syndrome, focusing on special outcomes like pain severity and functional outcomes. comparison will be done to check the effectiveness of Stecco-fascial Manipulation and Rolfing Structural Integration on patients of both groups. participants will: 1. get the treatment according to their respective groups 2. Both groups were given 4 sessions for 4 weeks.

Gender: All

Ages: 25 Years - 45 Years

Updated: 2026-01-07

1 state

Piriformis Syndrome
ACTIVE NOT RECRUITING

NCT07278193

Foam Rolling and Dynamic Stretching in Piriformis Syndrome

To compare the combined effects of foam rolling and dynamic stretching in patients with piriformis syndrome. 1. Warm-Up (2-3 minutes) Objective: Increase blood flow and prepare muscles for stretching. * Marching in Place - 30 seconds * Pelvic Tilts - 10 reps * Gentle Hip Circles - 10 reps each direction 2. Intervention Phase (8-10 minutes) Group 1: Foam Rolling Alone (FR) (\~10 minutes) * Piriformis Foam Rolling: 30-60 sec per side (2-3 sets) * Glutes \& Lower Back Foam Rolling: 30 sec each (2-3 sets) * Hamstrings \& IT Band Foam Rolling: 30 sec each (2-3 sets) Focus: Slow, controlled rolling with sustained pressure on tender spots. Group 2: Foam Rolling + Dynamic Stretching (FR+DS) (\~10-12 minutes) Step 1: Foam Rolling (\~5-6 minutes, same as Group 1) Step 2: Dynamic Stretching (\~5-6 minutes) * Dynamic Piriformis Stretch: Standing knee-to-opposite-shoulder pull (10 reps per leg) * Leg Swings: Forward and sideways (10 reps each leg) * Walking Lunges with Rotation: 10 reps per leg * Hip Circles \& Controlled Butt Kicks: 10 reps each 3. Cool-Down (2-3 minutes) Objective: Reduce muscle tension and promote recovery. * Seated Piriformis Stretch: 30 sec hold per side (2 sets) * Hamstring Stretch: 30 sec hold per leg * Lower Back Stretch (Child's Pose): 30 sec Progression \& Adjustments * Gradual increase in duration or intensity as tolerated. * Modify exercises if discomfort or pain occurs. * After week 4, increase dynamic stretch duration if flexibility improves. Outcome Measures The effectiveness of the intervention will be assessed through the following key outcome measures: 1. Pain Level - Evaluating changes in discomfort intensity during daily activities and movement. 2. Range of Motion (ROM) - Measuring improvements in hip flexibility and mobility.

Gender: All

Ages: 35 Years - 50 Years

Updated: 2025-12-11

1 state

Piriformis Syndrome
RECRUITING

NCT05023005

Strain-Counterstrain Treatment of Piriformis Pain

The purpose of this investigator-initiated study is to provide an efficient and non-invasive treatment option for pain caused by the piriformis muscle.

Gender: All

Ages: 18 Years - 65 Years

Updated: 2025-10-30

1 state

Low Back Pain, Mechanical
Piriformis Syndrome
Somatic Dysfunction of Sacral Region (Finding)
NOT YET RECRUITING

NCT07145554

f-ESWT vs Steroid Injection for Piriformis Syndrome

This study aims to compare two treatment methods for piriformis syndrome, a condition that can cause pain in the buttock and leg. Adult patients with piriformis syndrome will take part in the trial. Participants will be randomly assigned to one of two groups. One group will receive focal extracorporeal shock wave therapy (f-ESWT), a non-invasive treatment that uses sound waves. The other group will receive a steroid injection, which is a common treatment used to reduce pain and inflammation. The goal of this study is to find out which treatment is more effective in improving symptoms of piriformis syndrome.

Gender: All

Ages: 18 Years - Any

Updated: 2025-08-28

Piriformis Syndrome
RECRUITING

NCT07090356

Instrument-Assisted Soft Tissue Mobilization Versus PNF Stretching in Athletes With Piriformis Syndrome

A 12-month randomized controlled trial will be conducted at Pakistan Sports Board, Lahore, with 40 athletes (18-35 years) randomly allocated to IASTM (n=20) or PNF (n=20) groups. Interventions were administered 3 times/week for 4 weeks. Outcomes included Numeric Pain Rating Scale (NPRS), goniometric hip ROM, and Oswestry Disability Index (ODI).

Gender: All

Ages: 18 Years - 35 Years

Updated: 2025-07-29

1 state

Piriformis Syndrome
RECRUITING

NCT07044869

Effects of Facilitated Positional Release Technique ( FPRT) Vs Manual Myofascial Release Technique in Female Patients With Piriformis Syndrome.

This study is a randomized control trial, and the purpose of this study is to determine the "Effects of Facilitated Positional Release Technique ( FPRT) Vs Manual Myofascial Release Technique in Female Patients with Piriformis Syndrome.

Gender: FEMALE

Ages: 25 Years - 50 Years

Updated: 2025-07-01

Piriformis Syndrome
RECRUITING

NCT06102733

Chronic Pelvic Pain in Females and Males

Pelvic pain is under-reported in healthy adults. Many patients with pelvic pain under-estimate the problem. Chronic pelvic pain can be managed properly, if diagnosed promptly. This is a quantitative analysis of prospective clinical data. It evaluates the management of pelvic pain in a cohort population, and analyzes the treatment outcome.

Gender: All

Ages: 20 Years - 99 Years

Updated: 2025-01-27

1 state

Pelvic Pain Syndrome
Sacroiliac Disorder
Piriformis Syndrome
+2
RECRUITING

NCT06753487

"Effects of Facilitated Positional Release Technique( FPRT) Vs. Manual Myofascial Release Technique in Female Patients With Piriformis Syndrome

This study is a randomised control trial and the purpose of this study is to determine the "Effects of Facilitated Postional Release Technique( FPRT) Vs Manual Myofascial Release Technique in Female Patients With Piriformis Syndrome.

Gender: FEMALE

Ages: 25 Years - 50 Years

Updated: 2024-12-31

1 state

Piriformis Syndrome
RECRUITING

NCT06534788

Effects of Reciprocal Inhibition Versus Post Facilitation Muscle Energy Technique Along With Conventional Physical Therapy in Patients With Piriformis Syndrome: a Randomized Controlled Trial

This study is a randomized controlled trial and the purpose of this study is to compare the effects of reciprocal inhibition versus post facilitation muscle energy technique along with conventional physical therapy in patients with piriformis syndrome in terms of pain, range of motion at hip joint and functional disability.

Gender: All

Ages: 20 Years - 50 Years

Updated: 2024-08-02

1 state

Piriformis Syndrome
RECRUITING

NCT06460675

Comparasion of Autogenic Inhibition and Reciprocal Inhibition Muscle Energy Techniques (METS) in Piriformis Syndrome

To compare the effects of Autogenic Inhibition and Reciprocal Inhibition Muscle Energy Techniques (METS) in Piriformis Syndrome

Gender: All

Ages: 25 Years - 45 Years

Updated: 2024-06-14

1 state

Piriformis Syndrome
ACTIVE NOT RECRUITING

NCT06437795

Effectiveness of Dry Needling Versus Cupping Therapy for Pain in Piriformis Syndrome

This study aims to compare the effectiveness of two popular therapeutic interventions, dry needling and cupping therapy, in alleviating pain associated with Piriformis Syndrome. Piriformis Syndrome is a neuromuscular disorder caused by the compression or irritation of the sciatic nerve by the piriformis muscle, leading to buttock pain and radiating numbness.

Gender: All

Ages: 18 Years - 65 Years

Updated: 2024-05-31

1 state

Piriformis Syndrome
RECRUITING

NCT06437327

Comparison of Effectiveness Between Active Release Technique and Hold Relax Technique in Patients With Piriformis Syndrome

This study is a randomized controlled trial and the purpose of this study is to compare the effects between active release technique and hold relax technique in patients with Piriformis syndrome.

Gender: All

Ages: 25 Years - 55 Years

Updated: 2024-05-31

1 state

Piriformis Syndrome
RECRUITING

NCT06406023

Effectiveness of Instrument Assisted Soft Tissue Mobilization in Management of Piriformis Syndrome

This study aims to assess the effectiveness of IASTM on pain, ROM, Disability and Quality of life among Piriformis Syndrome patients. This study will add to the growing body of knowledge as there are very limited researches done in Pakistan using IASTM in patients with Piriformis Syndrome.

Gender: FEMALE

Ages: 30 Years - 65 Years

Updated: 2024-05-09

1 state

Piriformis Syndrome