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Primary Valvular Heart Disease With Comorbid Coronary Artery Disease

Tundra lists 1 Primary Valvular Heart Disease With Comorbid Coronary Artery Disease clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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NCT03977129

Quantitative Flow Ratio (QFR) Guided Coronary Artery Bypass Grafting for Patients Undergoing Primary Valve Surgery With Concomitant Coronary Artery Disease

This is a multicenter, prospective, randomized, blinded, controlled clinical study in patients with planned primary valvular surgery and comorbid coronary artery lesions with diameter stenosis of ≥ 50%, to compare the effectiveness of an Quantitative Flow Ratio (QFR)-guided revascularization strategy and a coronary angiography (CAG)-guided revascularization strategy in preventing the incidence of composite outcome (MACE-5, including all-cause death, myocardial infarction, stroke, unplanned coronary revascularization, and new renal failure requiring dialysis) within 30 days after surgery. The study hypothesis is that the QFR-guided strategy can reduce the incidence of the MACE-5 within 30 days after surgery, as compared with the CAG-guided strategy.

Gender: All

Ages: 18 Years - Any

Updated: 2025-09-17

8 states

Primary Valvular Heart Disease With Comorbid Coronary Artery Disease

Planned to Undergo Elective On-pump Valve Surgery Due to Primary Mitral and/or Aortic Valvular Heart Disease