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Clinical Research Directory

Browse clinical research sites, groups, and studies.

2 clinical studies listed.

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Pulse Oximetry

Tundra lists 2 Pulse Oximetry clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ACTIVE NOT RECRUITING

NCT06063148

Neonatal Pulse Oximetry Disparities Due to Skin Pigmentation

The goal of this clinical trial is to determine if pulse oximeters show an SaO2-SpO2 discrepancy that correlates with skin pigmentation such that pulse oximetry will overestimate oxygenation in newborns with darker skin. The main questions it aims to answer is if SaO2-SpO2 discrepancy varies with the degree of skin pigmentation among neonates, if gestational age has an influence on SaO2-SpO2 discrepancy, and if packed red blood cell (PRBC) transfusion has an influence on SaO2-SpO2 discrepancy in newborns with various degrees of light and dark skin. Researchers will compare SaO2 and SpO2 values in neonates of various skin pigmentation.

Gender: All

Ages: Any - 10 Days

Updated: 2026-02-20

2 states

Skin Pigment
Pulse Oximetry
ENROLLING BY INVITATION

NCT06298422

Oxygen Saturations Across Tones of Skin

Pulse oximetry, or SpO2, is a vital sign used across healthcare systems to gauge how much oxygen blood is carrying as a percentage of the maximum it could carry. Recent research has suggested that current SpO2 monitors may inaccurately report high SpO2 in patients with darker skin tones when the actual oxygenation is at unsafe, low levels. Additionally, this new research suggests as the SpO2 levels decrease, the risk of occult hypoxia rises. The investigators hypothesize melanin interferes with the pulse oximetry accuracy. Investigators will use spectrophotometry to measure melanin indices and other variables to test this hypothesis.

Gender: All

Ages: 18 Years - 99 Years

Updated: 2024-05-08

1 state

Generalised Melanin Pigmentation
Pulse Oximetry