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Clinical Research Directory

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3 clinical studies listed.

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TMJ Internal Derangement

Tundra lists 3 TMJ Internal Derangement clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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COMPLETED

NCT07750522

Correlation Between MRI Findings and Clinical Improvement Following TMJ Injection With Hyaluronic Acid and Platelet-Rich Plasma

Temporomandibular joint (TMJ) disorders can cause jaw pain, clicking sounds, and difficulty opening the mouth, affecting daily activities such as eating and speaking. This study aims to determine whether magnetic resonance imaging (MRI) findings can help predict how much patients improve after a single injection into the TMJ containing hyaluronic acid and platelet-rich plasma (PRP). Adults with TMJ internal derangement who have not improved with conservative treatment will receive one injection of hyaluronic acid combined with PRP prepared from their own blood. Participants will be evaluated before treatment and at follow-up visits over 6 months. Assessments will include pain, jaw function, mouth opening, and MRI scans before and after treatment. The results of this study may improve understanding of the relationship between MRI findings and treatment outcomes and help healthcare providers identify patients who are most likely to benefit from this minimally invasive therapy.

Gender: All

Ages: 18 Years - 45 Years

Updated: 2026-08-06

1 state

TMJ Internal Derangement
NOT YET RECRUITING

NCT07226505

Effects of Core Strengthening Exercises for Treating TMD

Temporomandibular disorders (TMD) are commonly managed with non-invasive interventions such as manual therapy, therapeutic exercise, relaxation techniques, and patient education. Core strengthening (also known as abdominal strengthening) is a fundamental element of physical therapy that engages deep and superficial trunk musculature to enhance postural control and functional performance. Protocols such as the Shirley Sahrmann progression have demonstrated increased activation of key core stabilizing muscles. Emerging evidence suggests a potential relationship between core stability training and reductions in TMD-related pain, though improvements in functional outcomes remain inconclusive. Biomechanical links between the pelvic floor, spine, and temporomandibular joint further support the rationale for core-focused interventions. Nevertheless, few studies have isolated the effects of core strengthening on TMD symptomatology. This study seeks to determine whether the integration of core stability exercises into TMD management can reduce pain, improve function, and enhance quality of life.

Gender: All

Ages: 18 Years - 80 Years

Updated: 2025-11-10

1 state

Temporomandibular Joint Dysfunction
TMD
TMJ Internal Derangement
+1
NOT YET RECRUITING

NCT06713356

US Vs MRI in Diagnosis of TMJ Internal Derangement

Compare the accuracy of ultrasonography and magnetic resonance imaging in the diagnosis of temporomandibular joint internal derangements.

Gender: All

Updated: 2024-12-03

TMJ Internal Derangement