Clinical Research Directory
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2 clinical studies listed.
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Tundra lists 2 Thrombotic Thrombocytopenic Purpura, Acquired clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.
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NCT07513948
Daratumumab in Immune-mediated Thrombotic Thrombocytopenic Purpura
Data about efficacy and safety of daratumumab in iTTP refractory or intolerant to standard immunosuppressive treatments are scarce. Therefore, the investigators aim at collecting evidence on a larger number of patients through a collaborative, international study.
Gender: All
Ages: 18 Years - 99 Years
Updated: 2026-04-07
NCT06928233
Association of TNFAIP3 With Immune-mediated TTP
This study aims to investigate whether genetic variation in the TNFAIP3 locus is associated with immune-mediated thrombotic thrombocytopenic purpura (iTTP), and whether such association is mediated by decreased expression of A20 (TNFAIP3). The study includes a case-control design to assess genotype-expression association and a cohort study to evaluate clinical outcomes such as disease relapse.
Gender: All
Ages: 12 Years - Any
Updated: 2026-03-27