Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

3 clinical studies listed.

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White Matter Disease

Tundra lists 3 White Matter Disease clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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RECRUITING

NCT03047369

The Myelin Disorders Biorepository Project

The Myelin Disorders Biorepository Project (MDBP) seeks to collect and analyze clinical data and biological samples from leukodystrophy patients worldwide to support ongoing and future research projects. The MDBP is one of the world's largest leukodystrophy biorepositories, having enrolled nearly 2,000 affected individuals since it was launched over a decade ago. Researchers working in the biorepository hope to use these materials to uncover new genetic etiologies for various leukodystrophies, develop biomarkers for use in future clinical trials, and better understand the natural history of these disorders. The knowledge gained from these efforts may help improve the diagnostic tools and treatment options available to patients in the future.

Gender: All

Updated: 2025-10-23

13 states

Leukodystrophy
White Matter Disease
Leukoencephalopathies
+63
RECRUITING

NCT05848271

Natural History Study of Patients with HPDL Mutations

This study uses medical records that allow retrospective data extraction of clinical manifestation to assess the natural history of HPDL mutations

Gender: All

Updated: 2025-03-30

1 state

Mitochondrial Encephalomyopathies
Hereditary Spastic Paraplegia
Spastic Paraplegia
+4
RECRUITING

NCT03624374

Natural History Study of Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation (LBSL)

In this study, we will conduct retrospective chart and imaging reviews and prospective longitudinal virtual assessments of individuals with LBSL.

Gender: All

Updated: 2024-07-03

1 state

Leukoencephalopathies
LBSL
Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation
+3