Clinical Research Directory

Improving Lifestyle Habits and Metabolic Health in Forensic Psychiatric Patients

Background:People in compulsory forensic psychiatric care experience high rates of metabolic syndrome, cardiovascular disease, and related lifestyle risk factors, yet structured preventive health interventions are uncommon in secure psychiatric settings. The Structured Health Dialogue (SHD), a Swedish primary care model for cardiovascular disease prevention, combines motivational interviewing with individualised risk assessment and tailored lifestyle advice. Objective:To evaluate the feasibility, acceptability, and preliminary effects of an adapted SHD intervention in forensic psychiatric inpatient care. Methods:This single-centre, parallel-group, randomized controlled feasibility trial will recruit 50 adults aged 18-64 years from a secure forensic psychiatric clinic in Sweden. Participants will be randomized (1:1) to SHD plus usual care or usual care alone. The SHD includes health screening, lifestyle assessment, personalised cardiovascular risk feedback, and tailored recommendations. Primary outcomes are recruitment, retention, dropout, and assessment completion rates. Secondary outcomes include changes in metabolic risk factors and patient-reported quality of life and functioning (EQ-5D-5L, Mental Fatigue Scale) from baseline to 12 months. Conclusion: This study will inform the feasibility and potential effectiveness of implementing structured, person-centred preventive health interventions in forensic psychiatric care, guiding the design of a future full-scale trial.

Digital Engagement for Lifelong Health

The DELPHI project (Digital Engagement for Lifelong Prevention and Health Improvement) aims to develop, implement, and validate an advanced digital platform for promoting well-being and personalized prevention of chronic non-communicable diseases in healthy adults. By integrating wearable sensors, artificial intelligence, federated learning, and the Human Digital Twin (HDT) paradigm, the DELPHI platform is designed to collect, analyze, and interpret multidimensional data in order to deliver dynamic and personalized recommendations for healthy lifestyles. The study adopts a multicenter, randomized controlled pilot design, with a maximum duration of 12 months per participant. A total of 200 healthy adults aged 18-65 will be recruited in Southern Italy (Sicily, Campania, and Basilicata) and randomly assigned to either: (1) an experimental group using the full DELPHI platform, including personalized recommendations, adaptive content, and continuous feedback; or (2) a control group using a basic version limited to passive monitoring. As a non-clinical primary prevention pilot study, DELPHI aims to assess the operational feasibility, usability, and acceptability of the platform in real-world settings, while also exploring preliminary signals of impact on health and lifestyle domains without confirmatory purposes. Secondary objectives include monitoring physiological indicators, adherence to the app and wearable devices, and evaluating the feasibility of implementing the platform in workplace environments. Data collection will rely on wearable devices, digital questionnaires, and behavioral analysis, with strong safeguards for personal data protection in compliance with GDPR and advanced security approaches such as federated learning and encryption. Specific subgroups, including workers from the Fondazione Don Carlo Gnocchi (FDG) as well as university staff and students, will be involved in targeted assessments related to mental well-being and distress. In addition, workers from the FDG will test a virtual reality module designed to evaluate biomechanical overload risks during manual handling activities in simulated environments. These additional physiological and virtual reality components are exploratory and non-diagnostic. Overall, DELPHI seeks to provide a solid foundation for the adoption of predictive and personalized models in digital health, contributing to the development of a sustainable and accessible prevention ecosystem, particularly in Southern Italy.

Active Schools in Chile: Impact on Fitness, Physical Activity, and Sports Participation

Study Rationale: Currently, a significant proportion of children in Chile do not meet recommended physical activity levels, which may adversely affect their health and development. The school environment provides an ideal setting to promote healthy habits. This study was designed to evaluate whether a school-based program incorporating physical activity, sports, and health education can improve physical fitness and increase the time children dedicate to physical activity practice. Objective: The primary objective of this study is to evaluate the impact of a two-year school-based intervention on physical activity levels, physical fitness (measured by upper body, lower body, and abdominal muscular strength), and sports participation among Chilean schoolchildren. How the study works: This study is a cluster-randomized clinical trial incorporating a control group and a pre-post design. Participating schools were allocated into two groups: Intervention Group: Participated in a specialized program focused on physical activity and the promotion of sports practice throughout two school years. Control Group: Continued with the standard school curriculum and regular physical education classes for the same period. What was measured: At baseline and after the two-year intervention, the following outcomes were assessed: Physical Activity Levels: Measured via accelerometry; Physical Fitness: Assessed through muscular strength tests, including upper limb strength (handgrip strength using a dynamometer), lower limb strength (standing long jump test), and abdominal strength (60-second curl-up test). Sports Participation: Evaluated through self-reports of involvement in organized sports. Researchers compared pre- and post-intervention data between the intervention and control groups to determine if children in the special program showed significantly greater improvements compared to those in the standard routine.

PURSUIT: A Technologically Augmented School-based Program to Improve Child Coping and Prevent Substance Use.

The study investigators aim to test an online support platform for Michigan youth aged 8-18 years enrolled in elementary, middle, or high school and their parent/caregiver. The online support platform will be hosted on the Computerized Intervention Authoring System (CIAS) 3.0 and will provide evidence-based cognitive behavioral coping skills for physical (pain) and mental (stress, mood) health symptoms, with additional substance use prevention content for youth aged 12 and older. Evaluations will occur at baseline and then a post assessment approximately 8 weeks later.

SCT-Based Health Promotion in Older Adults

This study will be conducted to compare the effects of Peer- and Nurse-Led Health Protection and Promotion Training Programs Based on Social Cognitive Theory (SCT) on the health behaviors of older adults. This research will be carried out in two stages as a mixed-methods study with an embedded mixed-method design. The first stage has been planned as a parallel two-arm non-randomized experimental study. This stage will be conducted between October and December 2025 in two separate elderly homes where older adults are densely located in the Muratpaşa district of Antalya province. The sample size has been calculated as 108 older adults (Intervention-1 Peer Leadership: 54, Intervention-2 Nurse Leadership: 54). In the Intervention-1 group, the intervention will be implemented for 12 weeks through the Health Protection and Promotion Training Program Based on SCT under peer leadership, and the same interventions will be carried out in the Intervention-2 group under nurse leadership. Outcomes will be measured before the intervention and 12 weeks after the intervention using the Elderly Health Promotion Scale, Health Protection and Promotion Behavior Checklist, General Self-Efficacy Scale, and Health Seeking Behavior Scale. In the second stage, in order to evaluate the intervention process and experiences multidimensionally, it is aimed to deeply understand the experiences of older adults receiving peer-led intervention, older adults receiving nurse-led intervention, and peer leaders by using multiple data sources within the framework of qualitative research and a phenomenological approach. In the qualitative phase, the data will be collected based on the maximum variation sampling method through face-to-face in-depth individual interviews using semi-structured interview forms in the workshops of both elderly homes in January 2026.

ePlatform for Promoting Health in Schools

There are few public health and educational policies specifically aimed at promoting physical activity, healthy dietary habits, and reducing sedentary behaviour among adolescents from socially disadvantaged backgrounds. ePro-Schools will co-design, pilot and evaluate an evidence-based program, delivered via a modular eHealth platform, to promote physical activity and healthy eating, and reduce time in sedentary behaviours. A profound co-creation process involving adolescents, school staff, and policymakers-alongside the adaptation of previous interventions by consortium members-will support the program's development. The ePro-Schools platform will contain modules for adolescents and their parents, teachers and school administration. Although the platform will be implemented through schools, it will include content to be implemented outside the school setting. The intervention program will be evaluated through a randomised controlled trial conducted in six secondary schools in Central Catalonia that aims to include 1000 adolescents. Schools have been randomised (1:1) into an intervention and a waiting-list control group. The evaluation of the program includes effectiveness, cost-effectiveness and process evaluation. Physical activity, sedentary behaviour and eating habits are the primary effectiveness outcomes of the trial. Secondary outcomes include fitness, water consumption, quality of life, depressive symptoms, social isolation and sleep quality. Using implementation science methodology, ePro-Schools will co-design transferable evidence-based practices and methodologies and guidance for scaling up the platform with policymakers and stakeholders, as well as informing specialists, policymakers and the general public.

Social Prescribing Intervention for Health Promotion in Community-Dwelling Older Adults

This study evaluates the effects of a social prescribing intervention on health promotion outcomes in community-dwelling older adults. The intervention consists of a 4-week mindfulness meditation program followed by a 12-week walking-pole exercise program. The purpose of the study is to determine whether this combined intervention improves physical function, psychological well-being, and sleep quality. Eligible participants aged 55 years and older will be enrolled from community settings and will receive the same 16-week intervention. Assessments will be conducted at baseline, after the mindfulness phase, after completion of the full intervention, and 3 months after the intervention ends. Study outcomes include physical function, mood, well-being, sleep quality, and indicators of continued participation and lifestyle change. The investigators hypothesize that the combined social prescribing intervention will lead to improvements in physical and psychological health among community-dwelling older adults and support healthy aging.

A Scalable, Teacher-delivered, School-based Oral Health Intervention for Pakistani Lower Secondary Schoolchildren

This was a pragmatic, two-arm, and parallel-group, superiority cluster-randomized controlled trial with 1:1 allocation of clusters (schools) to either the Smile Smarts-PK intervention arm or the control arm. The trial settings were lower secondary schools (classes 5-8) in the Punjab, Pakistan. Punjab is the most populous province of Pakistan; it has many public and low-cost private schools that serve lower- and middle-income communities.

The Effect of an Artificial Intelligence-Supported Health Promotion Application on the Nutrition, Exercise and Sleep Habits of Adolescents

The goal of this clinical trial is to learn if the "Smart Nurse" artificial intelligence-supported mobile application improves nutrition, exercise, and sleep behaviors in high school students aged 14-18 years. The main questions it aimed to answer are: * Did the "Smart Nurse" app improve healthy nutrition and exercise behaviors in adolescents? * Did the "Smart Nurse" app improve sleep quality in adolescents? * Did the "Smart Nurse" app lower body mass index (BMI) and waist circumference in adolescents? Researchers compared participants who used the "Smart Nurse" app to participants who did not use the app to see if the app improved health behaviors. Participants: * Used the "Smart Nurse" mobile app every day for 12 weeks * Recorded their daily meals, physical activity, and sleep time in the app * Received personalized health messages based on their data * Completed health surveys and body measurements at the beginning and end of the study

The Ku Ola Project: Enhancing Health Promotion Among Native Hawaiian Men.

The Ku Ola Project: The goal of this study is to determine if community-based discussion groups and small educational sessions enhance health awareness and behaviors among Native Hawaiian men. The study will examine if these interventions improve participants' health knowledge, attitudes, and self-efficacy while fostering local networks to support ongoing health promotion. Participants will engage in group discussions and educational sessions designed to build capacity and encourage healthy lifestyle choices.

Effects of Physical Activity Training on Physical Fitness and Quality of Life in Paramedic Students

Brief Title: Effects of an 8-week physical activity program in paramedic students (RCT) Official Title: EFFECTS OF PHYSICAL ACTIVITY TRAINING ON PHYSICAL FITNESS AND QUALITY OF LIFE IN PARAMEDIC STUDENTS This randomized controlled trial aims to examine the effects of regular physical activity training on physical fitness and quality of life in paramedic students. The study plans an eight-week physical activity program for paramedic students studying healthcare. The program will consist of exercises designed to improve physical endurance, muscle strength, flexibility, and overall physical performance. Main Hypothesis (H₁): Regular physical activity training will significantly improve the physical fitness level and quality of life of paramedic students. H₁a: Regular physical activity training increases the cardiovascular endurance of paramedic students. H₁b: Regular physical activity training significantly improves students' muscle strength and flexibility. H₁c: Students' body mass index (BMI) values are positively affected after regular physical activity training. H₁d: Students who participated in the physical activity program had significantly higher quality of life scores (SF-36 subscales) than the control group. This randomized controlled trial will test the effectiveness of an 8-week, 3-day-per-week physical activity program to assess physical fitness and quality of life in paramedic students. Participants will be randomly assigned to either the intervention (exercise program) or a standard-of-care/waiting control group. Primary outcomes include physical endurance (short form of the International Physical Activity Questionnaire (IPAQ)) and the SF-36 total score. Measurements will be taken at pre-intervention, after 8 weeks, and at 3-month follow-up. Study Type: Interventional. Allocation: Randomized. Intervention Model: Parallel Assignment. Masking: None Primary Outcome Measures: Change in physical endurance (distance, meters) with physical activity exercises - from baseline to week 8. Change in health-related quality of life by SF-36 total score - from baseline to week 8. Time Frame: Baseline, week 8, 3-month follow-up. The study suggests that regular physical activity-based training programs can improve both the professional resilience and quality of life of paramedic students. These findings are expected to contribute to the inclusion of physical activity-based modules in health education programs and positively impact the professional productivity of future paramedics.

Reframing Retirement: An Examination of Identity Change and Self-Regulation Approaches to Promote Physical Activity

The primary objective of this clinical trial is to test the efficacy of an innovative multimodal eHealth \& mHealth intervention (focused on emphasizing identity/habit and/or self-regulation) on increasing moderate to vigorous (MVPA) across 12 months among newly retired adults not meeting Physical Activity guidelines at study baseline, thus at higher risk of age-related chronic diseases. The secondary objectives are to examine whether these approaches improve physical and mental well-being and health related fitness-outcomes. Principal Research Question 1: Does an intervention focused on identity/habit + self-regulation skills + education (ID) increase moderate-to-vigorous intensity physical activity (MVPA) compared with an intervention focused on self-regulation skills + education (SR), and an education control condition (ED)? Three-arm parallel design single blinded randomized controlled trial. Participants will be randomized to one of three groups (ID, SR, ED) for 12 months duration. * After the initial screening process, eligible participants will be provided with an accelerometer-mailed or delivered in person-to wear for seven consecutive days. Data collected will verify baseline physical activity levels and determine final eligibility based on adherence to physical activity guideline thresholds. * Participants will visit the lab for fitness testing and complete an online questionnaire See below in "detailed description" the breakdown/delivery given for each of the 3 arms.

Teaching Health Resilience in a Hospital Setting: A Peer-led Intervention

The purpose of the study is to develop an acceptable, feasible, and effective peer-led bundle of health resilience and promotion services to be delivered in the hospital setting, called the THRIVE intervention. The main question it aims to answer is: Will participants receiving the THRIVE intervention have a reduced risk of self-reported non-fatal overdoses OR skin/soft tissue infections compared to participants receiving enhanced usual care? Researchers will compare the THRIVE model to enhanced usual care to see if the THRIVE model helps participants reduce their number of self-reported non-fatal overdoses OR skin/soft tissue infections. Intervention participants will: * Receive one in-person session from a peer support specialist while in the hospital * Receive weekly text messages from the peer support specialist for a 12-week period * Receive monthly, multiple-choice assessments via text message at Month 1, 2, 3, 4, 5, and 6 * Complete a baseline, 3-month, and 6-month assessment with Research Assistants Enhanced usual care participants will: * Receive a handout with health resilience education and resources in their local area * Receive monthly, multiple-choice assessments via text message at Month 1, 2, 3, 4, 5, and 6 * Complete a baseline, 3-month, and 6-month assessment with Research Assistants

A Comparative Intervention Study on Strategies for Fruit Distribution and Awareness Campaigns in Schools

This implementation study evaluates two strategies to increase fruit consumption among Swedish students. (1) installing fruit stands in schools and (2) combining fruit stands with a health-awareness campaign. The intervention is implemented in a set of participating schools, each following one of the predefined strategies. Students are asked to use a research app to photograph their meals and snacks during three data-collection periods before, during, and after the intervention. The study collects information on fruit intake, eating patterns, and the number of fruits taken from the stands to assess effectiveness and reduce food waste. The aim is to identify which strategy better supports healthy eating habits in school environments.

Health Impact 360: Advancing Physical, Social, and Mental Health Among Marginalized Communities for Cardiovascular Health Equity

The purpose of this clinical trial is to evaluate an evidence-based intervention, Health Impact 360, toward the promotion of cardiovascular health (CVH), including physical, mental, and social health outcomes, among adults living in marginalized communities. Study hypotheses include: * Participants in the Health Impact 360 intervention arm will have better CVH (i.e., a higher overall LE8 score) at the 16-week endpoint compared to the control. * Participants in the Health Impact 360 intervention arm will report better mental health (i.e., a lower perceived stress score) at the 16-week endpoint compared to the control. * Participants in the Health Impact 360 intervention arm will report better social support and well-being (i.e., higher emotional support and instrumental support scores and reduced social isolation) at the 16-week endpoint compared to control. * Participants with greater intervention engagement (e.g., better session attendance) will experience greater intervention impacts across all primary and secondary outcomes relative to the minimally engaged peers. Researchers will compare outcomes among intervention participants to outcomes among delayed intervention control participants who will be invited to participate in Health Impact 360 once all endpoint measures are collected. Participants will: * Engage in group-based programming twice per week for 8 weeks * Engage in group-based programming once per week for 8 weeks * Participate in survey-based and biometric data collection at two timepoints: baseline and 16-week endpoint * Self-monitor their physical activity via a study-provided pedometer

Dance-Mindfulness Intervention for Well-Being in Recreational Adults

This 12-week study protocol outlines a randomized controlled trial designed to evaluate the effectiveness of a Dance-Mindfulness intervention integrating Modern Theatre Dance with mindfulness-based embodied practices to enhance psychological wellbeing, nervous system regulation, and embodied awareness in adults. The intervention combines: (1) polyvagal-informed breath-movement synchronization (nasal breathing, grounding); (2) ISTD (Imperial Society of Teachers of Dancing) Modern Theatre Dance technique progression and dance movements (Grades 2-4); (3) nervous system regulation through somatic practices; and (4) phenomenological reflection via weekly journaling and post-session integration. Study Design: Parallel-assignment randomized controlled trial (approx. N=320; n=160 intervention, n=160 waitlist control). Randomization uses computer-generated block randomization (block sizes 4-6). Outcomes: Perceived stress, mindfulness psychological wellbeing (happiness, life satisfaction), emotional regulation, social connection, movement confidence. Qualitative Component: Phenomenological interviews and weekly reflective journals from subsample (approx. n=20) analyzed via Interpretative Phenomenological Analysis and Reflexive Thematic Analysis. Intervention Delivery: 90-100 minute weekly sessions delivered over 12 weeks by qualified facilitator(s) trained in Modern Theatre Dance, mindfulness (≥3 years personal practice, MBSR, yoga or equivalent), trauma-informed care, and group facilitation. Sessions include 8 structured components: breath-grounding (9-10 min), technical dance work (14-15 min), conditioning (9-10 min), break-settling (4-5 min), rhythm improvisation (8-9 min), choreographed sequences (15-17 min), cool-down-integration (8-9 min), and phenomenological journaling (10-20 min). Safety \& Fidelity: Structured facilitator guidelines, session checklists, weekly supervision, adverse event protocols, and external fidelity monitoring ensure protocol integrity. Classroom size: 15-18 participants per session. Data Collection: Baseline (Week 0), mid-intervention (Week 6 only for qualitative), post-intervention (Week 12), and optional 1-3 month follow-up. Intent to treat analysis and mixed-effects modeling for between-group comparisons. Population: Adults (age 18+) seeking wellbeing enhancement through recreation or stress reduction. Eligible participants without acute mental health crisis. Primary Purpose: Health promotion and mental health improvement through nervous system regulation, embodied awareness, and psychosocial wellbeing enhancement.

Effects of the Health Promotion Program on Health Literacy, Physical and Mental Health Status, and Quality of Life

This study aims to evaluate the physical and mental health status, prevalence of chronic diseases, health literacy, and health behaviors of residents in Gandaki Province, Nepal, and to assess the effectiveness of a community-based health promotion program integrating health education, exercise, and auricular acupressure. The intervention is designed to improve quality of life, health literacy, and chronic disease management among rural populations with limited healthcare access. This is a prospective interventional cohort study conducted over seven years (2025-2031) in two rural villages of Pokhara, Gandaki Province: Belchautara (experimental) and Rupakot (control). A total of 400 residents aged 19 years and older will be screened and enrolled (200 per village). Participants will be recruited through local nursing colleges and health centers. Year 1 involves mixed methods research (descriptive-correlational and qualitative) to identify community health needs. Years 2-7 will employ a quasi-experimental design with annual interventions and follow-up evaluations. Interventions 1. Health Education Program: Frequency: 12 weekly sessions (1 hour each), repeated three times per year. Content: hygiene, nutrition, stress management, lifestyle modification. Measures: health literacy, blood pressure, glucose, cholesterol, anthropometry, quality of life, and PHQ-9. 2. Exercise Program: Frequency: 8 weekly sessions (1 hour each), repeated three times per year. Activities: muscle stretching, sit-ups, push-ups, sit-to-stand, and grip strength training. Measures: Sit and Reach Test, push-up and sit-up counts, grip strength. 3. Auricular Acupressure: Indications: back pain, dysmenorrhea, or perimenopausal symptoms. Frequency: once per week for 2 weeks. Measures: Numeric Rating Scale (NRS), Oswestry Disability Index, Menstrual Distress Questionnaire, and Perimenopause Symptom Scale. Exclusion: pregnancy, metal allergy, or ear disease. Data will be collected at baseline and post-intervention through structured questionnaires and physical measurements.

Xylitol Gum for Promoting Smoking Cessation

The goal of this clinical trial is to learn if 4-week xylitol gum intervention works to promote smoking cessation in daily smokers. It will also learn about the feasibility and acceptability of using xylitol gum. The main questions it aims to answer are: （1）Does xylitol gum help to reduce cigarette consumption and promote smoking cessation? Researchers will compare 4-week xylitol gum intervention to the brief advice to see if xylitol gum works to promote smoking cessation. Participants in the intervention group will receive a 3-month behavioral intervention comprising a 4-week xylitol gum aligned with 12 weeks of instant reminder message support.

YoPA - A Youth-centred Participatory Action

Background A vast majority of adolescents do not meet guidelines for healthy physical activity, sedentary behaviour, and sleep, posing major risks for developing multiple non-communicable diseases. Unhealthy lifestyles seem more prevalent in urban than rural areas, with the neighbourhood environment as a mediating pathway linking urban living and poor health. How to develop and implement sustainable and effective interventions focused on adolescent health and wellbeing in urban vulnerable life situations is a key challenge and research gap. This paper describes the protocol of a Youth-centred Participatory Action (YoPA) project aiming to tailor, implement, and evaluate social and physical environmental interventions using an evidence-informed youth-centred co-creation approach, for structural improvement of the lifestyles of adolescents in urban vulnerable life situations. Methods In diverse urban environments in Denmark, the Netherlands, Nigeria, and South Africa, academic researchers will engage adolescents (12-19 years) growing up in vulnerable life situations and other key stakeholders (e.g., policy makers, urban planners, community leaders) in local co-creation communities. Together with academic researchers and local stakeholders, adolescents will take a leading role in mapping the local system for needs and opportunities; tailoring interventions to their local context; implementing and evaluating interventions during participatory meetings over the course of three years. YoPA applies a participatory mixed methods design guided by the newly developed SUPER-AIM framework assessing: (i) the local Systems, (ii) User perspectives, (iii) the Participatory co-creation process, (ii) Effects, iv) Reach, (vi) Adoption, (vii) Implementation, and (viii) Maintenance of interventions, in an integrated manner. Discussion YoPA aims to fill various research gaps, including the development of a practical protocol guiding the application of co-creation to tailor evidence-informed interventions to divers, multi-country contexts. Additionally, it focuses on advancing the research gap in physical activity and health within Sub-Saharan Africa and the involvement of adolescents in shaping their physical and social environments. Academic researchers envision that the YoPA co-creation approach will serve as a guide for participation of adolescents in vulnerable life situations in implementation of health promotion and urban planning in Europe, Africa and globally.

Qualitative Study Among Migrant and Socially Vulnerable Populations on Their Interest in Collective Approaches to Health Promotion.

This exploratory qualitative study aims to collect the health needs and representations of migrant and socially vulnerable populations attending the Doctors in the World center in Nice, and to assess their interest in collective approaches to health promotion. Semi-structured interviews were conducted between June and August 2025. Data are analyzed thematically to identify needs, barriers and facilitators to the implementation of collective health groups

The Effect of Health Education on Digital Game Addiction and Health Promotion Behavior in Adolescents

Nowadays, among adolescents who are frequently exposed to digital technologies, problematic behaviors resulting from misuse such as problematic internet use, video game addiction, and online gaming disorder are commonly observed (Young, 2017). In the literature, the prevalence of digital game addiction among adolescents has been reported to range between 0.7% and 15.6% (Arifin et al., 2022; Karadağ \& Noyan, 2023; Miezaha et al., 2020; Yudes et al., 2021). Promoting health-enhancing behaviors plays a key role in combating digital game addiction in adolescent health (Daysal \& Yılmazel, 2020). Previous studies have found that adolescents generally exhibit a moderate level of health-promoting behaviors (Özdemir \& Bülbül, 2023). When behaviors such as regular sleep, stress management, exercise, and adequate and balanced nutrition are adopted by adolescents with the aim of improving health, the need for technology tends to decrease (Bebiş et al., 2015; Özcan et al., 2023; Hysing et al., 2021). When the existing literature is reviewed, it appears that there is a lack of randomized controlled trials that explain behavior change as a process through health education aimed at promoting healthy behaviors among individuals affected by digital game addiction, which is considered a significant problem in adolescents (Shinde et al., 2020; Yang, 2020). In this context, the aim of this study is to determine the effect of health education provided to adolescents on digital game addiction and health-promoting behaviors. The population of the study consisted of 5th, 6th, 7th, and 8th grade students (n = 825) enrolled at Etimesgut 15 July Martyrs Secondary School located in the city center of Ankara. When the study was completed with 136 participants, a post hoc power analysis indicated that with an effect size of f = 0.25, the study achieved 80% power and 95% confidence (1-α) based on a four-group experimental design with repeated measures ANOVA, with a minimum of 34 participants per group (Cohen, 1992). Considering potential participant loss, the sample size was increased by 15%, and the study was initiated with 160 participants, allocating 40 to each group. The study will begin after obtaining permission from the Ankara Provincial Directorate of National Education and approval from the Ethics Committee. Following the identification of voluntary adolescents who meet the inclusion criteria, information about the study will be provided to both the adolescents and their parents, and written informed consent will be obtained. In this randomized controlled study based on the Solomon four-group design, participants will be assigned to groups using the block randomization method (Group 1: Intervention Group 1, Group 2: Intervention Group 2, Group 3: Control Group 1, Group 4: Control Group 2). Research data will be collected through a pretest administered to Group 1 (intervention 1) and Group 3 (control 1) immediately after randomization and prior to training, and a post-test administered to all groups at the end of the third month following the completion of the four training sessions. The intervention groups will receive a standardized health education program delivered over four sessions spanning three months. The timing of the training sessions will be coordinated with the school administration to fit within the school schedule. The data collection tools used in the study include the Descriptive Information Form (20 items), the Digital Game Addiction Scale for Children (24 items), and the Adolescent Health Promotion Scale (40 items). If the data do not follow a normal distribution, non-parametric methods will be used, and analyses will be conducted using the Walrus package in the JAMOVI software. For analyzing the relationships between scales, Pearson or Spearman correlation coefficients will be used depending on the normality of the data. For categorical data, if the expected frequency is greater than 25, Pearson's chi-square test will be applied; if it is between 5 and 25, Yates' correction will be used; and if it is less than 5, Fisher's exact test will be employed. For the analysis of numerical demographic data, one-way ANOVA will be used if the data are normally distributed, and the Kruskal-Wallis test will be used if not. IBM SPSS Statistics version 23 will be used for statistical evaluations. A significance level of p \< 0.05 will be considered statistically significant in this study.

Controlled Evaluation of an Exercise Program for Overweight Adolescents

Physical activity decreases as young people get older, especially during the shift from early to late adolescence. Unfortunately, around 81% of school-aged children worldwide between the ages of 11 and 17 do not meet the recommendation of at least one hour of physical activity per day - and this is also true in Switzerland. Not being active enough, whether normal weight or overweight, can lead to long-term health problems and is a major factor in becoming overweight over time. This results in healthcare costs and negatively affects quality of life. Supporting physical activity in overweight youth requires well-rounded, thoughtful programs. The investigators studying the impact of the movement programs now! and now!+ on the physical activity and health of young people. The goal is to look at both physical and mental changes equally. Taking part in this study involves minimal physical or mental risk for the participants. These small risks from the testing methods and activities are taken into account in how the program is explained and carried out. The benefits for the participants - feeling healthier and fitter physically, and more confident and capable mentally - clearly outweigh any potential risks, thanks to the additional, guided, and personalized exercise program. The participants take part in the now! and now!+ exercise programs run by the Basel-Stadt Sports Office and the DSBG. now! is a 90-minute group session with up to 14 young people, while now!+ is a 90-minute small-group session with 2 to 4 participants. Both programs take place once a week over a 12-month period and pause during school holidays (38 training weeks in total). Each session includes a warm-up, a strength or endurance training block, and a coordination phase. The program is modular and adapted to the physical and personal needs of each participant. This ensures that overweight adolescents are not overstrained and don't develop symptoms like pain, frustration, or lack of motivation (Behringer et al., 2011), while still allowing for a training stimulus that supports physical improvement. The results of the evaluations are directly used to improve and further develop the exercise program. The overall project includes three rounds, each consisting of one year of training and three test sessions, each lasting about two hours. The now! and now!+ programs are held weekly for a total of 38 weeks per year, with breaks during school holidays. Each of the three test sessions includes the same set of assessments (see "Study Intervention") and follows a set order: The process begins with measuring body size and blood pressure, followed by a static retinal vessel analysis. After these medical checks, participants do a 5-minute warm-up on a stationary bike at a set resistance level. Then, strength tests are performed: knee extension on the IsoMed 2000, handgrip strength, and jump power on the Leonardo force plate. The endurance test using spiroergometry marks the end of the physical assessments. Finally, impulse control is tested, and participants complete a set of questionnaires. At the end of the session, each participant is given an actigraph (a small motion sensor worn on the body) to track their physical activity over the following seven days.

A Service-Learning Program for Comprehensive Geriatric Assessment and Health Promotion in Older Adults

The GEROS Project aims to develop and implement a Service-Learning (S-L) program that integrates Comprehensive Geriatric Assessment (CGA) and health promotion, for students at the Faculty of Health Sciences and Welfare at the University of Vic - Central University of Catalonia (UVic-UCC). This initiative engages university students, healthcare professionals, and older adults (60+) in a participatory, intergenerational approach that fosters mutual learning and community engagement. The study follows a non-experimental mixed-method design, involving students from Nursing, Physiotherapy, Human Nutrition and Dietetics, Occupational Therapy, and Psychology. Participants include older adults (60+) who can independently travel to the university. The project is integrated into different subjects, in groups of 4-5 students, participants conduct a Comprehensive Geriatric Assessment (CGA), evaluating frailty using VIG-Frail, intrinsic capacity with ICOPE, quality of life with EUROQOL 5D-5L, and specific health indicators with Nursing Outcomes Classification (NOC). To assess the program's effectiveness, several outcome measures will be analyzed including students' perceived knowledge, competencies, and skills, as well as older adults' awareness of their health status, lifestyle, and risk factors. Additionally, the satisfaction levels of both will be evaluated. The items will be evaluated using a 1-5 Likert Scale, and the analysis will be conducted with SPSS. Data recording will be carried out through REDCap. The GEROS Project aligns with the United Nations' Sustainable Development Goals (SDGs), specifically SDG 3 (Good Health and Well-being) and SDG 10 (Reduced Inequalities). By offering care to the aging population and providing them with personalized health recommendations, the project promotes preventive strategies, active aging, and intergenerational learning. Furthermore, GEROS integrates innovative educational methodologies, encouraging experiential learning, collaboration with healthcare professionals, and the development of practical skills in real-world contexts. The program's scalability and adaptability could serve as a model for other universities and healthcare institutions aiming to enhance geriatric care through service-learning initiatives.

Blue-green Space Physical Activity: the "Parco Del Mare" Study

This study protocol, describe the innovative study intervention which will be performed in a green-blue space in Italy in order to investigate on the improvements in wellbeing following participation in the study. This will be significant because it will provide evidence on the effectiveness of the supervised physical activities carried out in green-blue space in improving health, quality of life, physical performance, anthropometric outcomes and physiological parameters in adults, indicating the reasonableness for public health authorities to developing such activities.