Clinical Research Directory

Wearable Sensors to Detect Atypical Muscle Activation in Young Infants

The purpose of this study is to see if wearable sensor technology can be used to evaluate muscle activity and/or identify atypical muscle tone in infants up to 48 weeks postmenstrual age (8 weeks corrected age). These sensors are placed on the surface of the skin and record data about a child's body movements and muscle activity.

Development of Human Motor Skills and the Promotion of Motivation for Physical Activity

This study is conducted within the University Centre of Excellence for Studies of Human Motoric at the Faculty of Physical Education and Sport, Charles University. The project focuses on research investigating mechanisms that support motivation for participation in physical activity among children and youth. In recent decades, participation in physical activity has been declining globally, including among children and adolescents. Understanding the factors that influence motivation for physical activity is essential for developing effective strategies to support long-term engagement in physical activity. The study aims to contribute to knowledge about the role of physical activity and physical education in promoting children's long-term physical and mental development.

Motor Competence and Physical Activity in Children Aged 4-6: Associations With Parental Perceptions

This study aims to determine motor competence and physical activity levels in children aged 4-6 years and to explore their relationship with parental perceptions. The study will use a qualitative research approach supported by quantitative assessments. Children's motor competence will be evaluated using the Peabody Developmental Motor Scales-Second Edition (PDMS-II), while parents will participate in semi-structured interviews to explore their perceptions, attitudes, and experiences related to their children's motor development and physical activity. Data will be collected in educational settings without any intervention. The findings are expected to contribute to a better understanding of family-related factors influencing motor development in early childhood.

Motor Development of Normal Children

The goal of this type of study: observational study is to compare motor development between urban and rural regions in pre-school age children. The main questions it aims to answer are: * Is there difference in gross motor development of normal children aged from four to six years between urban and rural areas? * Is there difference in fine motor development of normal children aged from four to six years between urban and rural areas? Participants will be asked to perform tasks of bruininks-oseretsky test of motor proficiency, second edition. Researchers will compare urban group and rural group to see if there is any difference in motor development.

Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia

The goal of this study is to understand the development and progression of childhood dystonia, a movement disorder, in children. The main questions it aims to answer are: How does the activity of the neural network evolve in children with dystonia in the context of motor development? What are the effects of chronic and active stimulation on cortical and subcortical motor network function in children with deep brain stimulation (DBS)? Participants will: * Undergo noninvasive electrophysiological measurements (EEG, EMG) to quantify neural network activity. They will be tested at rest and during a simple motor reaction task. * Children with DBS will be assessed in the on and off DBS state to assess effects of chronic and active changes in motor network function.

Are Developmentally At Risky Babies Environmentally Disadvantaged?

A study conducted on infants aged between 3 and 11 months revealed a positive relationship between the home environment and developmental outcomes. Similarly, another study found that variability in motor and cognitive development could be better explained by environmental factors and parental knowledge and practices. It has also been shown that the opportunities provided in the home environment of preterm infants may be associated with motor development and sensory processing skills. In the literature, it is generally observed that studies evaluate either term infants or both preterm and term infants together. In the present study, however, infants at developmental risk and typically developing infants will be evaluated separately. The aim of this study is to assess whether infants at developmental risk are disadvantaged in terms of their home environment. The hypotheses of this study are as follows: H1-1: There is a difference in environmental arrangements between typically developing infants and those at developmental risk. H1-2: There is a relationship between home environmental arrangements and motor development. H1-3: There is a relationship between home environmental arrangements and sensory profile.

Impact of Vestibular Function on Deaf Infants' Activities of Daily Living

This non-interventional study aims to assess the impact of vestibular impairments on the daily life activities of deaf children aged 0 to 2 years old. Three groups of participants will be included: deaf children with vestibular impairment, deaf children without vestibular impairment, and hearing children without vestibular dysfunction (control group). Children's daily activities will be evaluated through the OT Hope 0-5 years tool, a parent-administered questionnaire designed to measure competencies in different areas: personal care, play, and social interactions. This study also includes qualitative interviews with parents to further explore how vestibular impairments affect children's daily routines. It is hypothesized that: * Deaf children with vestibular impairments will show lower scores in daily life activities compared to the other two groups. * Deaf children without vestibular impairments will demonstrate scores closer to those of hearing children but may show some differences due to their hearing status. The research is conducted at the Robert Debré Hospital, in Paris, and aims to enroll 105 children over a three-year period. The data collected will provide insights into the specific needs of children with vestibular impairments and lay the groundwork for targeted early interventions.