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3 clinical studies listed.
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Tundra lists 3 Oral Squamous Cell Carcinomas clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.
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NCT05774483
Sentinel Node Biopsy Versus Limited Elective Neck Dissection in Early Cancers of Oral Cavity NoDe Negative
The goal of this clinical trial is to compare the survival outcomes, morbidity and cost-effectiveness of sentinel node biopsy versus limited elective neck dissection in node-negative early oral cancers. The main questions it aims to answer are: * Survival outcomes * Morbidity outcomes * Cost-effectiveness Participants will either undergo sentinel node biopsy followed by completion neck dissection if sentinel node is reported to be metastatic (SNB) or limited elective neck dissection where level IIb will be cleared only if level IIa is metastatic (limited END). The study will compare the outcomes in the two cohorts.
Gender: All
Ages: 18 Years - 80 Years
Updated: 2025-07-17
2 states
NCT06861036
Heterogeneity of Oral Squamous Cell Carcinoma Analysis by Single Cell RNA Sequencing
The goal of this project is to characterise the heterogeneity of all cell populations (tumour cells, stromal and immune microenvironment) present in the tumor and their normal (and leucoplasic) counterparts by scRNAseq in OSCC patients.
Gender: All
Ages: 18 Years - Any
Updated: 2025-03-06
NCT06425146
Tobacco, Alcohol and Cancerization of the Oral Mucosa (TACO)
The goal of this project is to describe somatic mutations of healthy oral mucosa from patients with oral squamous cell carcinoma (OSCC).
Gender: All
Ages: 18 Years - Any
Updated: 2024-08-22