Clinical Research Directory

Effects of Tai Chi and Dual Task Balance Training in Post Stroke Patients

The aim of the study is to compare the effects of Tai Chi and Dual Task Balance Training on Balance and Fall Risk in Post Stroke Patients

Indonesian Version of Oxford Cognitive Screen-Plus Test in Stroke Patient

The incidence of stroke increases every year throughout the world. Neuropsychological assessment is the best way to identify post-stroke cognitive dysfunction. The importance of cognitive function in the post stroke rehabilitation program process requires a tool that can detect cognitive disorders more specifically and more sensitively. The investigator aim in this study was to develop Indonesian version of the OCS - Plus among stroke patient in Indonesia.

Comparative Effects of SBES Versus TOT on Lower Limb Motor Function in Post-Stroke Patients

Stroke-induced lower limb impairments severely inhibit functional independence and mobility in survivors. Inventive techniques like Synergy-Based Electrical Stimulation (SBES) and Task-Oriented Training (TOT) support favorable rehabilitation results based on Neuroplasticity. This study aims to compare the effectiveness of these in restoring purposeful movements and enhancing motor functions in post-stroke patients.This study aims to compare the efficacy of (SBES) and Task-Oriented Training (TOT) in improving lower limb motor control in sub-acute post-stroke patients. This study will be a single-blinded randomized clinical trial design. Participants, aged 40-60 will be recruited in this study by Non-Probability convenience sampling from Rehabilitation centers and Neurology departments. Informed consent and consistent attendance throughout the intervention will be required. Through the computerized table generator method of randomization, participants will be evenly divided into two groups. Both groups will receive conventional therapy, like stretching, strengthening, and isometrics, with modalities. Group A will receive 30 Hz electrical stimulation on the affected lower limb muscles (hip flexors, knee flexors, and ankle dorsiflexors) in a synergic pattern, for 60 minutes, thrice weekly for 6 weeks. Group B will engage in functional tasks for 60 minutes, thrice weekly for 6 weeks, repeated 10 times per set with 2 sets of each activity, plus an additional self-practice session. Outcome measures will be assessed at baseline and post-intervention stages by the Fugl-Meyer Assessment for motor recovery, Time UP and Go Test (TUG) and 10 Meter Walk Test for functional mobility, gait, and balance. The paired sample t-test will be used for within-group analysis in the parametric data and the Wilcoxon test for non-parametric data, whereas, for between-group analysis independent t-test will be used for parametric data and Mann Whitney U test will be used for non-parametric data. Statistical analysis will be done by using SPSS version 26. Keywords: Lower Limb, motor control, SBES, Strength, Stroke, TOT.

An Ecological Momentary Assessment Based Program to Support Self-Management for Post-stroke Patients

The goal of this feasibility study is to test whether a new approach that combines real-time symptom tracking (Ecological Momentary Assessment) with machine learning can help people recovering from a stroke to better manage depression, thinking difficulties, and daily functioning. The main questions it aims to answer are: Is this combined approach practical and acceptable for post-stroke survivors? Does the program improve mood, cognitive function, or functional ability to carry out daily activities? Participants will: Use a smartphone app called RehabCare Companion for a period of time Answer brief daily surveys about their mood, thoughts, and activities for one week Receive personalized self-care suggestions generated by machine learning based on their responses Complete assessments of depression, cognition, and functioning before and after the program Take part in a group interview to share their experiences

PoRI Clinical Trial

This randomized clinical trial compares the Portable Rehabilitation Interface (PoRI) device for rehabilitation of hand motor function in post-stroke patients with conventional hand therapy.

Therapeutic Music Listening in Post Stroke Patients.

Numerous studies have highlighted how individualized music listening favors motor, cognitive, and emotional recovery in post-stroke patients, stimulating neuroplasticity and cerebral connectivity. However, gaps persist regarding the standardization of protocols and the neural mechanisms involved. This study aims to bridge these gaps with a rigorous scientific approach, integrating clinical assessments and neuroimaging. This is a multicenter randomized controlled single-blind trial. Subjects will be allocated into 2 groups: an experimental group subjected to a 4-week intervention of daily Therapeutic Music Listening sessions (Raglio, 2023) in addition to conventional therapeutic interventions (standard care), and a control group subjected solely to conventional therapeutic interventions (standard care). A follow-up is scheduled for one month after the conclusion of treatment. The study duration is 24 months and the screening phase will be continuous until the conclusion of planned recruitment. Primary objective of the study is to evaluate the efficacy of Therapeutic Music Listening (TML) on anxiety in post-stroke patients. Secondary objective of the study is to investigate other possible effects on depression, quality of life, cognitive aspects (specifically attention and memory), and on connectivity via functional Magnetic Resonance Imaging (fMRI). Primary endpoint is the reduction of anxiety. Secondary endpoint is the improvement in depression, quality of life, cognitive functions, and cerebral connectivity parameters.

Perception of Advanced Rehabilitation Technologies Among Post-Stroke Patients and Rehabilitation Staff

This observational study aims to assess the perception of advanced rehabilitation technologies among three key groups involved in stroke recovery: post-stroke patients, physicians specialized in Physical and Rehabilitation Medicine, and allied health professionals. The study is conducted at HCL - Renée Sabran Hospital , specifically within the Kermes 2 department. Participants are selected using a non-probability sampling method, based on predefined inclusion and exclusion criteria. Data will be collected using a structured, author-developed questionnaire designed to evaluate attitudes, perceived usefulness, ease of use, and intention to adopt technologies such as exoskeletons, social robots, wearable interactive devices, and biofeedback systems. The questionnaire is applied at a single time point after obtaining informed consent. This research responds to the growing integration of technology in neurorehabilitation and seeks to identify potential barriers or facilitators to its adoption in clinical practice. The hypothesis is that there is a significant difference in perception and acceptance of advanced rehabilitation technologies between the three groups, influenced by their respective roles, experience, and level of exposure to such technologies.

Combined Effects Of Sensory Integration And Vestibular Exercises On Post-Stroke Patients

The aim of this study is to determine the combined effects of sensory integration and vestibular exercise on dizziness, fall risk and quality of life.