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4 clinical studies listed.
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Tundra lists 4 Thalassemia Majors (Beta-Thalassemia Major) clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.
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NCT07509996
Risk Factors Affecting Growth in Thalassemic Children at AUCH
Thalassemia major is a hereditary hemoglobinopathy characterized by ineffective erythropoiesis and severe anemia, necessitating lifelong blood transfusions(1,2). Regular transfusions lead to iron overload, a primary driver of growth retardation in affected children. Iron accumulation in tissues like the pituitary and liver disrupts growth hormone secretion and insulin-like growth factor-1 production.
Gender: All
Ages: 12 Months - 18 Years
Updated: 2026-04-03
NCT07288762
Gonadal Function in Thalassemic Patient
Patient with transfusion depandant beta thalassemia with accumulation of iron in their body affect pituitary gland and gonades lead to impaired their functions .
Gender: MALE
Ages: 10 Years - 18 Years
Updated: 2025-12-17
NCT06980662
The Effect of Laughter Yoga in Beta Thalassaemia Major Patients: a Randomised Controlled Trial
The aim of this study was to evaluate the effects of laughter yoga on Fatigue, Depression-Anxiety-Stress, Sleep quality, Haematological values and Blood transfusion number in Beta Thalassemia Major patients.
Gender: All
Ages: 18 Years - 65 Years
Updated: 2025-05-20
NCT06734520
Clinical Study of Super Transplantation in the Treatment of Severe β-thalassemia
This is a single-arm, open label, phase 1 study in subjects with beta-thalassemia. This study will evaluate the safety and efficacy of preconditioning-free super-transplantation on beta-thalassemia pediatric patients.
Gender: All
Ages: 7 Years - 10 Years
Updated: 2024-12-16
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