Clinical Research Directory

ACL Mechanical Property Changes in Female Collegiate Basketball Players During a Competitive Season

This prospective cohort study aims to investigate whether the mechanical properties of the anterior cruciate ligament (ACL) undergo measurable changes throughout a competitive basketball season in female collegiate athletes. Female athletes are at a significantly higher risk for non-contact ACL injuries compared to males. Beyond acute injuries, cumulative stress from high-intensity sports may lead to subclinical alterations in the ligament's biomechanical properties, potentially increasing injury risk. Using non-invasive shear wave elastography (SWE) and countermovement jump (CMJ) tests, the study will monitor 60 elite players before and after the University Basketball League (UBL) season. The findings will help identify potential signs of cumulative loading and contribute to the development of early detection markers for injury risk in female athletes.

Different Drop Height Plyometric Training in Soccer Players

This randomized controlled trial aims to determine the effects of different drop height plyometric training protocols on lower limb explosive strength, anaerobic power, and change of direction (COD) performance in soccer players. A total of 56 competitive soccer players aged 18-30 years will be randomly allocated into three intervention groups using sealed envelope randomization: low drop height (30 cm), moderate drop height (45 cm), and high drop height (60 cm) plyometric training groups. Participants will undergo supervised plyometric training three times per week for six weeks. Outcome measures including Vertical Jump Test, Running-Based Anaerobic Sprint Test (RAST), and T-Test Agility Test will be assessed at baseline and post-intervention. Statistical analysis will be performed using SPSS version 25 to determine within-group and between-group differences.

Acute Effects of Isometric Conditioning on Sprint, Jump and Change of Direction Performance in Youth Soccer Players

This study aims to examine the acute effects of an isometric conditioning activity on sprinting, jumping, and change-of-direction performance in elite youth soccer players. Twelve male soccer players aged 15-19 years from a professional academy will participate in a randomized crossover study. Each participant will complete two experimental sessions separated by one week. During each session, participants will perform a standardized warm-up followed by baseline performance tests including countermovement jumps, drop jumps, a 30-m sprint test, and a 505 change-of-direction test. After baseline testing, participants will complete one of two conditions in randomized order: (1) an isometric conditioning activity consisting of unilateral standing isometric calf raises, or (2) a control condition consisting of low-intensity treadmill walking. Performance tests will be repeated seven minutes after the intervention to assess acute changes in neuromuscular performance. Jump performance will be assessed using a dual force plate system sampling at 1000 Hz, and sprint performance will be measured using electronic timing gates. The study will be conducted on an indoor athletics runway located in a gymnasium. The results will help determine whether isometric conditioning activities can acutely enhance explosive performance in youth soccer players.

Effect of Foot Core Exercises on Jump Performance in Professional Volleyball Players

Brief Summary The purpose of this study is to investigate the effect of foot core exercises on jump performance in professional volleyball players. Participants will be randomly assigned to two groups. The first group will perform a strength training program only, while the second group will perform foot core exercises in addition to the same strength training program. Jump performance will be assessed using the Countermovement Jump (CMJ) test, and performance scores will be obtained through force-time analysis using the ForceDecks system. The findings of this study are expected to contribute to the development of training programs aimed at improving performance and reducing injury risk in professional volleyball players.

Impact of Mindfulness on Athletic Performance and Functional Movement in Collegiate Athletes

The goal of this clinical trial is to evaluate the effectiveness of a mindfulness training program on sports performance and mental health in university basketball players. The main questions it aims to answer are: 1. Does the mindfulness program improve basketball skills, body movement control, and psychological health? 2. Does the program's effectiveness differ between male and female athletes? 3. Is there an association between athletes' current psychological states and their athletic performance before training? Researchers will compare a mindfulness group to a psychological skills training group and a standard control group to see if the mindfulness program leads to significantly greater improvements in performance and well-being. Participants will: 1. Complete surveys about their mental health and stress. 2. Perform physical fitness tests, such as jumping, running, and strength exercises. 3. Perform basketball skill tests, including shooting, dribbling, and passing. 4. Play in standardized 5-on-5 basketball games that are video-recorded for analysis . 5. Attend 15-to-20-minute training sessions 3 times a week for 8 weeks (if assigned to a training group) .

Dynamic Q Angle and Core Endurance in Adolescent Athletes With Patellofemoral Pain Syndrome

This cross-sectional observational study aims to compare trunk mobility, lower extremity flexibility, and functional balance performance across different sports branches in adolescent elite male athletes. Trunk mobility will be assessed using a digital inclinometer in flexion, extension, and rotational movements; hamstring flexibility will be evaluated using the Straight Leg Raise test; and functional balance will be measured using the normalized Y-Balance Test. The study seeks to identify sport-specific biomechanical characteristics and potential indicators related to injury risk and performance adaptations in adolescent competitive athletes.

The Effects of Neuromuscular Training on Knee Biomechanics During Jump-Landing Among College Basketball Players Post ACL Reconstruction and Rehabilitation

Basketball players often injure the anterior cruciate ligament (ACL), a key structure that stabilizes the knee. Even after surgery and standard rehabilitation, many athletes continue to have problems with knee stability, movement control, and performance during jumping and landing. These issues increase the risk of re-injury and can limit their ability to return to competition. Neuromuscular training (NMT) is a type of exercise program that focuses on improving balance, muscle coordination, and movement patterns. It uses activities such as jump-landing drills, balance tasks, agility exercises, and core training. Previous research shows that NMT can help athletes land more safely, reduce harmful knee movements, and improve sport performance. However, little is known about its long-term benefits in college basketball players who are more than one year post-ACL surgery. This study aims to evaluate whether a 12-week NMT program, added to standard basketball training, can improve knee biomechanics, stability, and performance in college basketball players with a history of ACL reconstruction. Thirty participants will be randomly assigned to either an NMT group or a control group. Both groups will complete basketball training, but only the NMT group will receive the additional neuromuscular exercises. Knee movement will be measured using 3D motion capture and force plates, and performance will be tested through vertical jumps and other sport-specific tasks. The main outcomes will include knee angles during landing, ground reaction forces, dynamic stability, and jump height. The expected outcome is that athletes who undergo NMT will demonstrate safer landing strategies, better knee control, and improved performance compared to those who only receive standard basketball training. These findings may help coaches and healthcare providers design safer, more effective rehabilitation programs for athletes after ACL surgery.

Whole-Body Photobiomodulation Use in Professional Soccer Players During a State Championship

This study aims to investigate the effects of whole-body photobiomodulation on professional soccer players during a state championship. The primary question is whether photobiomodulation improves recovery, reduces muscle fatigue, and enhances performance compared to standard training without photobiomodulation.

Effects of Magnesium L-Threonate on Sleep, Recovery, and Athletic Performance in Collegiate Athletes

This study is testing whether a special form of magnesium called magnesium L-threonate can help improve sleep quality, recovery, and physical performance in college athletes. Magnesium is important for muscle recovery and sleep, but many forms of it do not enter the brain well. Magnesium L-threonate is unique in that it can cross the blood-brain barrier and may improve deep and REM sleep, heart rate variability, and brain recovery. In this study, healthy UCLA varsity athletes aged 18 to 35 will be randomly assigned to take either magnesium L-threonate or a placebo each evening for 4 weeks. They will wear a WHOOP strap to track sleep, recovery, and heart rate data. Performance tests including jump height, grip strength, and reaction time will be completed before and after the 4-week period. This study will help researchers determine if this supplement can support recovery and training in athletes and whether wearable technology can help monitor these changes in real time.

The Effect of a Training Programme in the Variation of Fitness Parameters, Physiological, Hematological and Biochemical Indicators of Soccer Players During the Preseason Period

The goal of this study is to investigate the effects of varying friendly match-play exposure during the late pre-season on physiological, biochemical, and performance adaptations in soccer players. It is hypothesized that (i) significant changes will occur across the pre-season in both the extended- and limited-play groups when analysed independently; (ii) distinct group-specific adaptations will emerge by the end of the preparatory period; and (iii) match-play exposure, when analysed across all participants, will be significantly correlated with physiological and performance outcomes at pre-season completion. Players from a randomly selected team will be assessed at three time points: pre-season start, mid-pre-season (MPS), and pre-competition phase (PC). Assessments will include anthropometry, physical performance, and markers of muscle damage, inflammation, hormonal status, and haematology. Based on the total match-play time of 8 friendly games during the late pre-season, players will be retrospectively categorised into extended-play (EP) and limited-play (LP) cohorts.time of 8 friendly games during the late pre-season, players will be retrospectively categorised into extended-play (EP) and limited-play (LP) cohorts.

The Impact of the Menstrual Cycle on Physical Exercise and Performance

The menstrual cycle implies a basic difference in the biology of women and men but the effect of the hormonal variation on training protocols and physical performance is still not fully understood. Despite no existing evidence, the advice to periodize exercise according to the menstrual cycle has been widely spread among elite athletes, coaches, and sports federations. The advice is based on underpowered studies with considerable methodological weaknesses regarding determination of cycle phase, inclusion of athletes and lack of adequate control groups. The purpose of this randomized, controlled study is to evaluate the effect of exercise periodization on aerobic fitness during different phases of the menstrual cycle. Further, the effect will be related to premenstrual symptoms, body composition and skeletal muscle morphology, sex hormone receptors, metabolic enzymes, and markers of muscle protein synthesis. This study will be well controlled and follow methodology recommendations for menstrual cycle research in sports and exercise. Female athletes of fertile age will be randomized to different training regimens during three menstrual cycles (12 weeks): Group A: Training three times a week throughout the menstrual cycle. Group B: Follicular phase-based training five times a week during the follicular phase and thereafter once a week during the luteal phase. Group C: Luteal phase-based training five times a week during the luteal phase and once a week in the follicular phase. The exercise will consist of high intensity intermittent spinning classes. Assessment of aerobic fitness and power will be performed at baseline, and again after three completed menstrual cycles. On the same day, body composition will be examined by DXA and blood samples will be collected for analysis of hormones and binding proteins. To confirm menstrual cycle phase, blood samples will be collected for hormone determination, and urinary stick will be used for detection of ovulation. Subjective ratings of menstrual cycle related symptoms will be performed every day. In a subgroup of women, muscle biopsies will be collected from m vastus lateralis at baseline and at the end of the study. This study will contribute to improved knowledge about exercise periodization in relation to the menstrual cycle. Well-grounded data is crucial to give evidence-based recommendations to female athletes when planning their training protocol to optimize training results and performance.

Effects of Neuroathletic Training on Judokas' Physical, Cognitive, and Performance Abilities

The primary objective of this project is to comprehensively investigate the effects of the Neuroathletic Training (NAT) approach, integrated into the routine training program, on the physical fitness, cognitive skills, and sports performance of judokas aged 10 to 18 years. This study is designed as a randomized controlled trial involving 40 judokas randomly assigned to either the NAT group or the control group. The NAT program, implemented over eight weeks, includes exercises targeting visual-motor coordination, reaction time, balance, and proprioception. Outcome measures such as reaction time, agility, balance, flexibility, proprioception, attention, grip strength, and judo-specific physical fitness will be assessed using a pre-test and post-test design. The results are expected to contribute to the development of a novel training model aimed at enhancing judo performance and to provide original insights into the effects of neuroathletic training in sports sciences. Additionally, the NAT protocol aims to improve not only physical fitness parameters but also cognitive domains such as mental flexibility, decision-making speed, and concentration by enhancing neuromotor control parameters including balance, coordination, reaction time, and attention.

Decoding Gut-Brain Biomarkers and Developing a Minimally Intrusive Gut Microbiome Sampling: Enhancing Cognitive Well-being in Athletes

The objective of this study is to assess the impact of a psychobiotic supplement on the gut health, neurological markers, and behavior of younger soccer players over the soccer season.

Plyometrics vs PAPE Training in Football: Effects on Agility, Explosive Power and Speed

The goal of this clinical trial is to compare the effects of 8 week plyometric training and post-activation performance enhancement (PAPE) training on explosive power, agility, acceleration and sprint speed, muscle strength and flexibility in healthy male semi-professional football players aged 18-35. The main questions it aims to answer are: Does PAPE training have effects on performance metrics of football players when planned and applied long-term (8 weeks)? Does long term PAPE training improve agility, acceleration and speed, flexibility, vertical jump height, and muscle strength more effectively than Plyometric training? Is there a significant difference in performance gains between PAPE and plyometric training compared to a control group receiving only routine football training? Researchers will compare a plyometric training group, a PAPE training group, and a control group to determine which method most effectively enhances football-specific performance outcomes. Participants will: * Be randomly assigned to one of three groups (Plyometric, PAPE, or Control) * Continue their routine football training as usual * Receive additional training sessions applied immediately after warm-up and before continuing regular team training alongside the Control group (for PAPE and Plyometric group) * Undergo an 8-week training program (3 times per week for Plyometric and PAPE groups) Assessments will be conducted at baseline, week 4, and week 8, including: * Vertical Jump Test (explosive power) * 30-Meter Sprint Test, including 10-meter acceleration recording * Illinois Agility Test * Isometric strength measurements of quadriceps, hamstrings, and gastrocnemius using a handheld dynamometer * Sit and Reach Test and Modified Thomas Test (flexibility) In addition, all participants will complete a sociodemographic and lifestyle assessment form capturing: Age, height, weight, BMI Football experience and playing position Education level, employment status Sleep duration, training frequency, and training intensity Smoking and alcohol use status.

Study on How Pre-Workout Supplements Affect Shooting Accuracy in Trained Basketball Players

Basketball is a popular team sport where athletes score points by successfully shooting the ball into the basket. Accuracy in shooting is crucial for players to score points effectively. Pre-workout supplements (PWS) have garnered interest from athletes and fitness enthusiasts due to the purported synergistic action of their ingredients which, when consumed before training, may help improve athletic performance. The acute effect of PWS or similar on the shooting accuracy of basketball athletes has not yet been investigated. Therefore, this study aimed to investigate the acute effect of a caffeine-based PWS (containing caffeine, creatine, β-alanine, citrulline malate, and BCAAs) on the stationary free throw, two-point, and three-point shooting accuracy in basketball players.

A Randomized Crossover Study on Diverse Training Methods to Enhance University Athletes' Performance and Health

The goal of this randomized crossover study is to investigate the effects of plyometric training, functional training, and whole-body electrical muscle stimulation (WB-EMS) on athletic performance and health in university basketball and volleyball players. The main questions it aims to answer are: 1. Which training modality (plyometric, functional, or WB-EMS) leads to the greatest improvements in athletic performance measures such as power, speed, and agility? 2. How do these training modalities compare in terms of their effects on overall health, injury risk reduction, and psychological well-being? Researchers will use a crossover design, where each participant experiences multiple training modalities in a sequential manner, to provide a more rigorous and comprehensive evaluation of the interventions' effectiveness. Participants will: 1. Be randomly assigned to one of four training sequences, each consisting of two 8-week intervention periods separated by a 4-week washout phase; 2. Experience at least two of the three training modalities (plyometric, functional, or WB-EMS) during the intervention periods; 3. Maintain their regular training routines if assigned to the control group; 4. Undergo assessments, including anthropometric measurements, physical fitness tests, and questionnaires, at baseline, after each intervention period, and during a follow-up session. The findings of this study will provide valuable insights into the optimal sequencing and combination of training modalities to maximize athletic performance and promote health among university basketball and volleyball players.

Balance Training To Enhance Stability And Athletic Performance During The Menstrual Cycle

This study was done to investigate the effect of balance training on improving balance and athletic performance during menstrual cycle in young athletic females Does balance training improve balance and athletic performance during the menstrual cycle? 60 athletic females will participate in the study. They will be randomly assigned into two groups. Group A will receive balance training on biodex, while group B will be the control group.